366003-68-1

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 109-73-9 N-butylamine 
• 366003-57-8 (+)-(2S)-methyl 2-(2-chloroacetylamino)-3-hydroxypropanoate 

Relevant academic research and scientific papers

(1-Benzylpiperazin-2-yl)methanols: Novel EPC synthesis from (S)-serine and transformation into ligands for central nervous system receptors

A novel three-step synthesis of 4-substituted-(1-benzylpiperazin-2-yl)methanols 5a-5c is described starting from the methyl ester of the proteinogenic amino acid (S)-serine, which involves the diastereomeric oxazolidine derivatives 11a-11c as key intermed

Chiral, nonracemic (piperazin-2-yl)methanol derivatives with σ-receptor affinity

Starting with the proteinogenic amino acid (S)-serine a series of chiral nonracemic (piperazin-2-yl)methanols 3 with various N-4 substituents is described. The key step in the synthesis of 3 is the reaction of the chloroacetamide 5 with various primary am