3663-97-6 Usage
Uses
Used in Pharmaceutical Industry:
AcetaMide, N-[4-(3-chloro-1-oxopropyl)phenyl]is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into the structure of various drugs, enhancing their therapeutic properties and effectiveness.
Used in Agrochemical Industry:
In the agrochemical industry, AcetaMide, N-[4-(3-chloro-1-oxopropyl)phenyl]is utilized as an intermediate in the production of agrochemicals, contributing to the development of more effective pesticides and other agricultural chemicals.
Used in Organic Synthesis:
AcetaMide, N-[4-(3-chloro-1-oxopropyl)phenyl]is employed in organic synthesis for its versatility in forming various chemical compounds, which can be used in a wide range of applications, from pharmaceuticals to materials science.
Used as a Reagent in Chemical Reactions:
AcetaMide, N-[4-(3-chloro-1-oxopropyl)phenyl]also serves as a reagent in various chemical reactions, facilitating specific transformations and processes that are essential in the synthesis of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 3663-97-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,6 and 3 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3663-97:
(6*3)+(5*6)+(4*6)+(3*3)+(2*9)+(1*7)=106
106 % 10 = 6
So 3663-97-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H12ClNO2/c1-8(14)13-10-4-2-9(3-5-10)11(15)6-7-12/h2-5H,6-7H2,1H3,(H,13,14)
3663-97-6Relevant academic research and scientific papers
Scaffold oriented synthesis. Part 2: Design, synthesis and biological evaluation of pyrimido-diazepines as receptor tyrosine kinase inhibitors
Gracias, Vijaya,Ji, Zhiqin,Akritopoulou-Zanze, Irini,Abad-Zapatero, Cele,Huth, Jeffrey R.,Song, Danying,Hajduk, Philip J.,Johnson, Eric F.,Glaser, Keith B.,Marcotte, Patrick A.,Pease, Lori,Soni, Nirupama B.,Stewart, Kent D.,Davidsen, Steven K.,Michaelides, Michael R.,Djuric, Stevan W.
, p. 2691 - 2695 (2008/12/21)
We report the discovery of the pyrimido-diazepine scaffolds as novel adenine mimics. Structure-based design led to the discovery of analogs with potent inhibitory activity against receptor tyrosine kinases, such as KDR, Flt3 and c-Kit. Compound 14 exhibited low nanomolar KDR enzymatic and cellular potencies (IC50 = 9 and 52 nM, respectively).
