36648-35-8Relevant academic research and scientific papers
Greener Paal-Knorr Pyrrole Synthesis by Mechanical Activation
Akelis, Liudvikas,Rousseau, Jolanta,Juskenas, Robertas,Dodonova, Jelena,Rousseau, Cyril,Menuel, Stphane,Prevost, Dominique,Tumkeviius, Sigitas,Monflier, Eric,Hapiot, Frdric
, p. 31 - 35 (2016)
A straightforward and solventless synthesis of pyrroles was developed by using mechanochemical activation and a biosourced organic acid as the catalyst. Relative to traditional Paal-Knorr methodologies, various N-substituted pyrroles were obtained in very short reaction times. By reaction with unreactive diketones, desymmetrized aliphatic and aromatic compounds were also synthesized.
