36651-81-7 Usage
Uses
Used in Pharmaceutical Industry:
5-Methyl-8-hydroxycoumarin is used as an intermediate in the synthesis of Bucumolol (B689395), which is an antihypertensive agent and a β-adrenoceptor blocker. Its role in the synthesis process is crucial, as it contributes to the development of a medication that helps in the treatment of hypertension and related cardiovascular conditions. 5-methyl-8-hydroxycoumarin's structural features make it a valuable building block for creating more complex and effective pharmaceutical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 36651-81-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,6,5 and 1 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 36651-81:
(7*3)+(6*6)+(5*6)+(4*5)+(3*1)+(2*8)+(1*1)=127
127 % 10 = 7
So 36651-81-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H8O3/c1-6-2-4-8(11)10-7(6)3-5-9(12)13-10/h2-5,11H,1H3
36651-81-7Relevant academic research and scientific papers
13C-NMR Spectra and Carbon-Proton Coupling Constants of Variously Annulated Furocoumarins
Guiotto, A.,Manzini, P.,Chilin, A.,Pastorini, G.,Rodighiero, P.
, p. 649 - 656 (2007/10/02)
The 13C-nmr spectra of variously annulated methylfurocoumarins are reported.The assignemnts of chemical shifts for all the C resonances has been achieved by using carbon-proton coupling constants, relaxation efficiency considerations and shift effects caused by the introduction of methyl groups at various positions of the furocoumarin nucleus.Substituent effects on 13C chemical shifts and carbon-proton coupling constants are discussed.
