36677-73-3Relevant academic research and scientific papers
Thermal pericyclic tandem reactions
Hopf, Henning,Wolff, Joachim
, p. 4009 - 4030 (2007/10/03)
Gas phase thermal isomerizations of twelve acetylenic systems, all of which can in principle undergo two successive pericyclic steps, are described. The substrates, the syntheses and spectroscopic properties of which are presented, are formal derivatives of but-2-yne, with different functional groups in the 1- and the 4-positions. The Cope, Claisen, Claisen ester, retro-ene, 1,5-hydrogen shift, and 1,5-homo hydrogen-shift processes were employed as the pericyclic steps from which the tandem processes were composed. The compositions of the pyrolysates obtained were determined over broad temperature ranges, and the mechanisms of the individual steps producing the pyrolysis products are discussed.
Hydration of Alkynes in Anhydrous Medium with Formic Acis as Water Donor
Menashe, Naim,Shvo, Youval
, p. 7434 - 7439 (2007/10/02)
Formic acid has been found to hydrate alkynes in the absence of water to give oxo products and carbon monoxide.The scope of the reaction of alkynes and formic acid has been delineated.Hydrocarbon alkynes were found to be reactive in the absence of catalyst.Functionalized alkynes, in particular oxygenated alkynes, are inert toward formic acid but can be activated catalytically with Ru3(CO)12.Consequently, all the tested types of alkynes were found to give oxo products and CO with formic acid.The mechanism of the reaction was examined.With some alkynes, the primary oxo products underwent secondary reactions that gave rise to unexpected products.
