36680-17-8Relevant academic research and scientific papers
An efficient synthesis of 2-quinoxalinecarboxylic acid
Harms, Arthur E.
, p. 666 - 669 (2004)
Development of a cost efficient and scaleable process for 2-quinoxalinecarboxylic acid is described. The primarily goals of the development work were to improve the overall yield of the process, to minimize the use of environmentally unacceptable material
Asymmetric hydrogenation of 2-and 2,3-substituted ouinoxalines with chiral cationic ruthenium diamine catalysts
Qin, Jie,Chen, Fei,Ding, Ziyuan,He, Yan-Mei,Xu, Lijin,Fan, Qing-Hua
supporting information; experimental part, p. 6568 - 6571 (2012/02/13)
The enantioselective hydrogenation of 2-alkyl- and 2-aryl-subsituted quinoxalines and 2,3-disubstituted quinoxalines was developed by using the cationic Ru(η6-cymene)(monosulfonylated diamine)(BArF) system in high yields with up to 99% ee. The counteranion was found to be critically important for the high enantioselectivity and/or diastereoselectivity.
Asymmetric hydrogenation of quinoxalines with diphosphinite ligands: A practical synthesis of enantioenriched, substituted tetrahydroquinoxalines
Tang, Weijun,Xu, Lijin,Fan, Qing-Hua,Wang, Jun,Fan, Baomin,Zhou, Zhongyuan,Lam, Kim-Hung,Chan, Albert S. C.
supporting information; experimental part, p. 9135 - 9138 (2010/02/28)
An easily accessible chiral lr/H8-binapo catalyst exhibits unprecedented reactivity and excellent enantioselectivity in the hydrogenation of quinoxalines at a high ratio of substrate to catalyst (from 100 to 20000). This new method provides a p
