366800-26-2

Upstream product

• 366800-18-2 2-[(E)-(7S,8S)-8-Allyloxy-7-hydroxy-9-(4-methoxy-benzyloxy)-non-1-enyl]-6-methoxy-benzoic acid methyl ester 
• 3147-64-6 2-hydroxy-6-methoxybenzoic acid 
• 22833-69-8 methyl 6-methoxysalicylate 
• 79439-15-9 methyl trans-2-nonen-8-ynoate 
• 173043-70-4 (E)-2-nonen-8-yn-1-ol 
• 145645-18-7 methyl 2-methoxy-6-{[(trifluoromethyl)sulfonyl]oxy}benzoate 
• 366800-07-9 1-Methoxy-4-[((E)-non-2-en-8-ynyl)oxymethyl]-benzene 
• 366800-09-1 (4S,5S)-4-(hex-5-ynyl)-5-{[(4-methoxybenzyl)oxy]methyl}-2,2-dimethyl-2,3-dioxolane 
• 366800-12-6 methyl 2-methoxy-6-{(1E)-6-[(4S,5S)-5-{[(4-methoxybenzyl)oxy]methyl}-2,2-dimethyl-1,3-dioxolan-4-yl]hex-1-enyl}benzoate 
• 366800-16-0 methyl 2-{(1E,7S,8S)-7,8-dihydroxy-9-[(4-methoxybenzyl)oxy]non-1-enyl}-6-methoxybenzoate 

Relevant academic research and scientific papers

Synthesis of a model system for the macrocyclic subunit of the oximidines

Cross-coupling reaction of aryl triflate 1 and vinyl stannane 13 provided salicylic acid derivative 15. This compound was converted to the dihydroxy acid 16, which provided in a size-selective macrolactonization the two macrolides 17 and 18 in a ratio of 60:40. Compound 17 is a model of the macrocyclic core of the oximidines.