36685-84-4

Basic information

• Product Name: Acetic acid, [4-(chlorosulfonyl)phenoxy]-, ethyl ester
• CAS NO: 36685-84-4
• Molecular Formula: C10H11ClO5S
• Molecular Weight: 278.713
• Mol File: 36685-84-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Acetic acid, [4-(chlorosulfonyl)phenoxy]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [4-(chlorosulfonyl)phenoxy]-, ethyl ester(36685-84-4)
• EPA Substance Registry System: Acetic acid, [4-(chlorosulfonyl)phenoxy]-, ethyl ester(36685-84-4)

Safety Data

• Hazardous Substances Data: 36685-84-4(Hazardous Substances Data)

Upstream product

• 2555-49-9 phenoxyacetic acid ethyl ester 
• 98-67-9 p-hydoroxybenzenesulfonic acid 
• 105-36-2 ethyl bromoacetate 
• 825-90-1 sodium p-hydroxybenzenesulfonate 
• 863545-83-9 (4-Sulfo-phenoxy)-acetic acid ethyl ester 

Downstream Products

• 591775-08-5 (4-Mercapto-phenoxy)-acetic acid ethyl ester 
• 98996-93-1 (4-methylsulfamoyl-phenoxy)-acetic acid 
• 181780-02-9 (4-{[Bis-(2-tert-butoxycarbonylamino-ethylamino)-methylene]-sulfamoyl}-phenoxy)-acetic acid ethyl ester 
• 181780-05-2 (4-{[Bis-(2-tert-butoxycarbonylamino-ethylamino)-methylene]-sulfamoyl}-phenoxy)-acetic acid 
• 760981-60-0 ethyl {4-{2-{4-[(bispyridin-2-ylmethylamino)methyl]-1H-benzimidazol-2-yl}phenylsulfamoyl}phenoxy}acetate 
• 760981-62-2 ethyl {4-{2-{4-[(methylpyridin-2-ylmethylamino)methyl]-1H-benzimidazol-2-yl}phenylsulfamoyl}phenoxy}acetate 
• 760981-58-6 ethyl {4-{2-{4-[(diethylamino)methyl]-1H-benzimidazol-2-yl}phenylsulfamoyl}phenoxy}acetate 
• 867339-08-0 {4-[2-(4-hydroxymethyl-1H-benzoimidazol-2-yl)-phenylsulfamoyl]-phenoxy}-acetic acid ethyl ester 
• 760981-55-3 ethyl {4-[2-(4-formyl-1H-benzimidazol-2-yl)phenylsulfamoyl]phenoxy}acetate 
• 760981-56-4 ethyl {4-[2-(1H-benzimidazol-2-yl)phenylsulfamoyl]phenoxy}acetate 
• 760981-54-2 2-(4-(N-(2-formylphenyl)sulfamoyl)phenoxy)acetic acid ethyl ester 
• 863483-25-4 [4-((1S,2S)-2-tert-Butoxycarbonylamino-1,2-diphenyl-ethylsulfamoyl)-phenoxy]-acetic acid ethyl ester 
• 863483-26-5 [4-((1S,2S)-2-tert-Butoxycarbonylamino-1,2-diphenyl-ethylsulfamoyl)-phenoxy]-acetic acid 
• 942614-42-8 2-(4-(N-(6-formylbenzo[1,3]-dioxol-5-yl)sulfamoyl)phenoxy)acetic acid ethyl ester 

Relevant articles and documents

Modulation of imine chemistry with intramolecular hydrogen bonding: Effects from ortho-OH to NH

Salicylaldehyde derivatives and their imines are important building blocks in organic and supramolecular chemistry. In an effort to expand structural diversity in the current work we changed ortho-OH in salicylaldehyde to NH of amide/sulfonamide and investigated the effect of resulting intramolecular hydrogen bonds on imine dynamic covalent chemistry (DCC). A suite of ortho-aminobenzaldehydes were readily synthesized, and X-ray and NMR data validated the existence of NH?O intramolecular hydrogen bonds. The formation and exchange of imines were then studied in acetonitrile, and the acidity of OH/NH significantly influenced the thermodynamics and kinetics of imine reactions. Furthermore, the role of OH/NH?N hydrogen bonds on imines was elucidated by the shift of aldehyde exchange equilibrium. Finally, the formation of imines was achieved in aqueous solutions. The mechanistic insights could pave the way for future applications in assembly and labelling.

BICYCLIC DERIVATIVES AS PPAR MODULATORS

The present invention is directed to compounds represented by the following structural formula, Formula (I), and stereoisomers, pharmaceutically acceptable salts, solvates and hydrates thereof, wherein: (a) R2 is selected from the group consisting of C0-C8 alkyl and C1-4- heteroalkyl; (b) X is selected from the group consisting of a single bond, O, S, S(O)2 and N; (c) U is an aliphatic linker wherein one carbon atom of the aliphatic linker is optionally replaced with O, NH or S, and wherein such aliphatic linker is optionally substituted with from one to four substituents each independently selected from R30; (d) Y is selected from the group consisting of C, O, S, NH and a single bond; and (e) E is C(R3)(R4)A or A.

FUSED HETEROCYCLIC DERIVATIVES AS PPAR MODULATORS

The present invention is directed to compounds represented by the following structural formula, Formula I: wherein (a) X is selected from the group consisting of a single bond, O, S. S(O)2 and N; (b) U is an aliphatic linker; (c) Y is selected from the group consisting of C, O, S, NH and a single bond; (d) E is C(R3) (R4)A or A and wherein (i) A is selected from the group consisting of carboxyl, tetrazole, C1-C6 alkylnitrile, carboxamidek, sulfonamide and acylsulfonamide; (e) B is selected from the group consisting of S, O, C, and N; (f) Z is selected from the group consisting of N and C; with the proviso that when B is C then Z is N.