3669-32-7

Basic information

• Product Name: cinnamoylhydroxamic acid
• Synonyms: cinnamoylhydroxamic acid;Benzeneacrylohydroximic acid;Cinnamohydroxamic acid;N-Hydroxy-3-phenyl-2-propenamide
• CAS NO: 3669-32-7
• Molecular Formula: C₉H₉NO₂
• Molecular Weight: 163.19
• Mol File: 3669-32-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 290.25°C (rough estimate)
• Flash Point: °C
• Appearance: /
• Density: 1.2021 (rough estimate)
• Refractive Index: 1.5460 (estimate)
• CAS DataBase Reference: cinnamoylhydroxamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: cinnamoylhydroxamic acid(3669-32-7)
• EPA Substance Registry System: cinnamoylhydroxamic acid(3669-32-7)

Safety Data

• Hazardous Substances Data: 3669-32-7(Hazardous Substances Data)

Usage

General Description

Cinnamoylhydroxamic acid is a chemical compound that belongs to the class of hydroxamic acids. It is derived from cinnamic acid, which is found in cinnamon and other plants. Cinnamoylhydroxamic acid has been studied for its potential use in pharmaceuticals and various industrial applications due to its diverse biological activities, including its ability to inhibit certain enzymes and its potential as a metal ion chelator. cinnamoylhydroxamic acid has also shown promise in the field of cancer research, as it has exhibited cytotoxic and anti-proliferative effects on cancer cells. Overall, cinnamoylhydroxamic acid is a versatile chemical with potential applications in various fields, making it an interesting subject for further research and development.

InChI:InChI=1/C9H9NO2/c11-9(10-12)7-6-8-4-2-1-3-5-8/h1-7,12H,(H,10,11)/b7-6+

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 599-71-3 piloty's acid 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 102-92-1 cinnamoyl chloride 
• 140-10-3 cis-cinnamic acid 
• 103-26-4 methyl cinnamate 
• 108761-28-0 (carbonic acid ethyl ester)-cinnamic acid-anhydride 
• 621-82-9 Cinnamic acid 
• 1138-15-4 1-(3-phenyl-acryloyl)-1H-imidazole 

Downstream Products

• 54891-84-8 1-(4-nitro-phenyl)-2-(3-styryl-[1,4,2]dioxazol-5-yl)-ethanone 
• 80-05-7 BPA 
• 66437-42-1 1-(3-styryl-[1,4,2]dioxazol-5-yl)-pentan-2-one 

Relevant articles and documents

Synthesis, characterization and spectrophotometric determination of vanadium(V) with unsubstituted cinnamoyl hydroxamic acid

A series of hydroxamic acid and their derivatives play a key role in chemistry and metallochemistry in the subject of study of many synthetic experimental investigations. In this paper the synthesized compound were characterized and their structure was co

Water mediated procedure for preparation of stereoselective oximes as inhibitors of MRCK kinase

Stereoselective aldoximes, preferably Z form have been obtained from α-cyano substituted carbonyl conjugated alkenes. This reaction occurs through Michael addition type reaction followed by retro-Knoevenagel reaction without transition-metal catalysis via C–C bond cleavage. These oximes are evaluated against cancer cell lines employing mechanistic study. Two oximes showed significant cytotoxic activity, which through in silico studies were found to inhibit MRCK Kinase, responsible for metastatic spread of cancer mortality.

Benzoic hydroxamate-based iron complexes as model compounds for humic substances: Synthesis, characterization and algal growth experiments

A series of monomeric and dimeric FeIII complexes bearing benzoic hydroxamates as O,O-chelates has been prepared and characterized by elemental analysis, IR spectroscopy, UV-Vis spectroscopy, electrospray ionization mass spectrometry (ESI-MS), cyclic voltammetry, EPR spectroscopy and for some examples by X-ray diffraction analysis. The stability of the synthesized complexes in pure water and seawater was monitored over 24 h by means of UV-Vis spectrometry. The ability to release iron from the synthesized model complexes has been investigated with algae growth experiments.