36695-19-9

Basic information

• Product Name: LiptiniteLiptobiolithLiqcoumarin
• CAS NO: 36695-19-9
• Molecular Weight: 218.209
• Mol File: 36695-19-9.mol

Chemical Properties

• CAS DataBase Reference: LiptiniteLiptobiolithLiqcoumarin(CAS DataBase Reference)
• NIST Chemistry Reference: LiptiniteLiptobiolithLiqcoumarin(36695-19-9)
• EPA Substance Registry System: LiptiniteLiptobiolithLiqcoumarin(36695-19-9)

Safety Data

• Hazardous Substances Data: 36695-19-9(Hazardous Substances Data)

Upstream product

• 2373-34-4 5-hydroxy-4-methylcoumarin 
• 108-24-7 acetic anhydride 
• 108170-46-3 5-acetoxy-4-methylcoumarin 
• 7446-70-0 aluminium trichloride 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 141-97-9 ethyl acetoacetate 
• 98-95-3 nitrobenzene 
• 10025-87-3 trichlorophosphate 
• 71-43-2 benzene 

Downstream Products

• 89152-33-0 10-methyl-2-phenyl-pyrano[2,3-f]chromene-4,8-dione 
• 1071667-81-6 6-acetyl-4-methyl-5-o-toluoyloxy-coumarin 
• 162711-88-8 5-hydroxy-6-(4-methoxy-trans-cinnamoyl)-4-methyl-coumarin 
• 89152-17-0 6-acetyl-5-benzoyloxy-4-methyl-2H-2-oxobenzopyran 
• 89152-18-1 4-Methoxy-benzoic acid 6-acetyl-4-methyl-2-oxo-2H-chromen-5-yl ester 
• 162711-89-9 6-[(E)-3-(3,4-Dimethoxy-phenyl)-acryloyl]-5-hydroxy-4-methyl-chromen-2-one 
• 855160-84-8 6-cinnamoyl-5-hydroxy-4-methyl-coumarin 

Relevant articles and documents

An efficient and practical procedure for the synthesis of 4-substituted coumarins

BiCl3 is used as an efficient catalyst in the Pechmann condensation reaction of phenols with β-keto esters leading to the formation of coumarin derivatives in excellent yields under solvent-free conditions. Georg Thieme Verlag Stuttgart.

Poly(4-vinylpyridine)-supported sulfuric acid: An efficient solid acid catalyst for the synthesis of coumarin derivatives under solvent-free conditions

Poly(4-vinylpyridine)-supported sulfuric acid is an efficient catalyst for the Pechmann condensation of acetoacetic esters with phenols, leading to the formation of coumarins in good yields within a few minutes under solvent-free microwave conditions. The catalyst used can be recovered and reused after activation. Springer-Verlag 2011.

Synthesis of novel α-pyranochalcones and pyrazoline derivatives as Plasmodium falciparum growth inhibitors

Both the lack of a credible malaria vaccine and the emergence and spread of parasites resistant to most of the clinically used antimalarial drugs and drug combination have aroused an imperative need to develop new drugs against malaria. In present work, α

The indium(III) chloride-catalyzed von Pechmann reaction: A simple and effective procedure for the synthesis of 4-substituted coumarins

Indium(III) chloride is used as an efficient catalyst in the von Pechmann condensation of phenols with β-ketoesters leading to the formation of coumarin derivatives in excellent yields with good purity.

Pechmann reaction in chloroaluminate ionic liquid

Substituted coumarins were synthesized in good yields via the Pechmann reaction in chloroaluminate ionic liquid. 1-Butylpyridinium chloroaluminate ionic liquid was used as a solvent cum catalyst for this condensation reaction.

Coumarin syntheses via Pechmann condensation in Lewis acidic chloroaluminate ionic liquid

1-Butyl-3-methylimidazolium chloroaluminate, [bmim]Cl·2AlCl3 ionic liquid is used as an alternative to conventional acid catalysts in the Pechmann condensation of phenols with ethyl acetoacetate leading to the formation of coumarin derivatives. The reaction time is reduced drastically even at ambient conditions. The ionic liquid plays the dual role of solvent and Lewis acid catalyst providing a quick and efficient route to the syntheses of coumarins.