36697-16-2Relevant academic research and scientific papers
Iron(III) Chloride Catalyzed Nucleophilic Substitution of Tertiary Propargylic Alcohols and Synthesis of Iodo-3H-Pyrazoles
Liu, Xiao-Tao,Ding, Zong-Cang,Ju, Lu-Chuan,Tang, Zhao-Ning,Wu, Feng,Zhan, Zhuang-Ping
, p. 620 - 624 (2017)
A straightforward and concise method was developed for the efficient and rapid synthesis of iodo-3H-pyrazoles by the FeCl3/I2-mediated propargylic substitution of tertiary propargylic alcohols with p-toluenesulfonyl hydrazide and subsequent cyclization under mild conditions. The method constitutes a novel approach to the synthesis of various iodo-3H-pyrazoles with a wide substrate scope and in high yields.
Synthesis, structure, and in vitro anti-HIV activity of new pyrazole, 1,2,4-thiadiazole, and 1,2,4-triazole derivatives
Al-Soud
experimental part, p. 2621 - 2636 (2009/09/06)
α,α'-Dichloroazo compounds 6 react with Lewis acid to furnish 1-(chloroalkyl)-1-aza-2-azoniaallene salts 4. The cations 4 react with acetylenes, isothiocyanates, isocyanates, and carbodiimides under [3+2]-cycloaddition. The cycloadducts undergo consecutiv
Investigations on Diazo Compounds and Azides, XXXVII. Diazo Group Transfer onto 2,3-Diphenylthiirene 1,1-Dioxide with Diazoalkanes.
Regitz, Manfred,Mathieu, Bernd
, p. 1632 - 1636 (2007/10/02)
The thiirene 1,1-dioxide 6 reacts with diazoalkanes (2a - d) not only under diazo group transfer to give 9a or 10b and c but also under loss of sulfur dioxide to form pyrazoles (11b, c and 8d).The bicycles 7 are intermediates of both reactions.
