367249-64-7Relevant academic research and scientific papers
Structural Analysis and Optimization of NK1 Receptor Antagonists through Modulation of Atropisomer Interconversion Properties
Albert, Jeffrey S.,Ohnmacht, Cyrus,Bernstein, Peter R.,Rumsey, William L.,Aharony, David,Alelyunas, Yun,Russell, Daniel J.,Potts, William,Sherwood, Scott A.,Shen, Lihong,Dedinas, Robert F.,Palmer, William E.,Russell, Keith
, p. 519 - 529 (2007/10/03)
We have previously described a series of antagonists that showed high potency and selectivity for the NK1 receptor. However, these compounds also had the undesirable property of existing as a mixture of interconverting rotational isomers. Here
Novel n-( 2-phenyl-3-aminopropyl)naphtamides
-
Page/Page column 8, (2010/02/05)
A compound of the formula wherein R1, R2, R3, R4, R5, R6, X1 and X2 are as defined in the specification useful for the treatment of diseases in which action of the neu
