367258-92-2

Upstream product

• 1484-26-0 3-(benzyloxy)aniline 
• 367260-94-4 4-nitrophenyl 3-(benzyloxy)phenylcarbamate 

Downstream Products

• 367258-95-5 (5S,8S,10R)-5-Cyclohexyl-3,6-dioxo-11,15-dioxa-2,4,7-triaza-tricyclo[14.3.1.1^7,10]henicosa-1⁽¹⁹⁾,16⁽²⁰⁾,17-triene-8-carboxylic acid 
• 367260-96-6 (5S,8S,10R)-5-Cyclohexyl-3,6-dioxo-11,15-dioxa-2,4,7-triaza-tricyclo[14.3.1.1^7,10]henicosa-1⁽¹⁹⁾,16⁽²⁰⁾,17-triene-8-carboxylic acid methyl ester 

Relevant academic research and scientific papers

P2-P4 Macrocyclic inhibitors of hepatitis C virus NS3-4A serine protease

Synthesis and HCV NS3 serine protease inhibitory activity of 4-hydroxyproline derived macrocyclic inhibitors and SAR around this macrocyclic core is described in this communication. X-ray structure of inhibitor 38 bound to the protease is discussed.