36749-56-1

Usage

Type of compound

Chemical compound (synthetic)

Potential applications

Pharmaceutical research and organic synthesis

Core structure

Cyclopentadienylidenindandione

Substituents

Two tert-butyl groups attached to the cyclopentadienyl ring

Extensive study

Limited (requires further research)

Unique structure

Suggests potential applications in new drug or material development

Current understanding

Insufficient, more research needed to explore its potential

Upstream product

• 955012-42-7 C₃₇H₄₄O₄ 
• 135979-37-2 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-3-hydroxy-1,4-naphthoquinone 
• 74-88-4 methyl iodide 

Relevant academic research and scientific papers

Dynamic equilibrium between dissociation and regeneration of the C-C bond in trispiro-conjoined cyclopropane compound

-The oxidation of 2,2-di(3,5-di-t-butyl-4-hydroxyphenyl)indan-1,3-dione by potassium hexacyanoferrate(III) afforded a trispiro-conjoined cyclopropane compound due to the bond formation between the ipso-carbons. Its cyclopropane ring was found to exist in solution in dynamic equilibrium with biradical species by the dissociation of the C-C bond, which is as long as 1.595 ? as revealed by X-ray crystal analysis.

On the reaction of the 5-lipoxygenase-inhibitor 2-(3,5-di-tert-butyl-4- hydroxyphenyl)-3-hydroxy-1,4-naphthoquinone with Mel/Ag2O

The reaction of the title compound 1, a selective 5-lipoxygenase inhibitor, with Mel/Ag2O results in a mixture of 3 by ring contraction and 6/7 by epoxidation. 3 is the main product up to now isolated only in traces by the reaction of 1/2 with