367516-93-6Relevant academic research and scientific papers
Chemoenzymatic synthesis of sulfated O-linked oligosaccharides: Epitopes for MECA-79
Bélot, Frederic,Rabuka, David,Fukuda, Minoru,Hindsgaul, Ole
, p. 7743 - 7747 (2007/10/03)
Sulfated oligosaccharides I, II and III, representatives of those found on L-selectin counterreceptors, have been efficiently prepared employing a combination of chemical and enzymatic synthetic methods.
Efficient synthesis of lactosaminylated core-2 O-glycans
Misra, Anup Kumar,Fukuda, Minoru,Hindsgaul, Ole
, p. 2667 - 2669 (2007/10/03)
A series of lactosaminylated oligosaccharides found in mucin type O-glycans was synthesized using a generalized block strategy. The synthesis involved the addition of a protected lactosamine donor to a partially protected T-disaccharide derivative. The nonreducing galactose residues of the deblocked oligosaccharide products could be removed by β-galactosidase from jack bean to produce the corresponding GlcNAc terminated compounds. A series of tri- to hexasaccharides was thus efficiently produced.
