36793-27-8

Basic information

• Product Name: 7,7,9,9-tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane
• Synonyms: 1,4-dioxa-8-azaspiro[4.5]decane, 7,7,9,9-tetramethyl-; 7,7,9,9-Tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane; 7,7,9,9-Tetramethyl-1,4-dioxa-8-aza-spiro[4.5]decane
• CAS NO: 36793-27-8
• Molecular Formula: C₁₁H₂₁NO₂
• Molecular Weight: 199.2899
• Mol File: 36793-27-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 255.9°C at 760 mmHg
• Flash Point: 105.6°C
• Density: 1.02g/cm³
• Vapor Pressure: 0.0159mmHg at 25°C
• Refractive Index: 1.488
• CAS DataBase Reference: 7,7,9,9-tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane(CAS DataBase Reference)
• NIST Chemistry Reference: 7,7,9,9-tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane(36793-27-8)
• EPA Substance Registry System: 7,7,9,9-tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane(36793-27-8)

Safety Data

• Hazardous Substances Data: 36793-27-8(Hazardous Substances Data)

Upstream product

• 826-36-8 2,2,6,6-Tetramethyl-4-piperidone 
• 107-21-1 ethylene glycol 

Downstream Products

• 68579-55-5 7,7,9,9-tetramethyl-1,4-dioxa-8-aza-spiro[4.5]decane-8-carboxylic acid (2-hydroxy-2,2-diphenyl-ethyl)-methyl-amide 
• 68579-56-6 7,7,9,9-tetramethyl-1,4-dioxa-8-aza-spiro[4.5]decane-8-carboxylic acid (2-hydroxy-2-phenyl-ethyl)-methyl-amide 
• 72152-32-0 7,7,9,9-tetramethyl-8-(3-phenyl-heptanoyl)-1,4-dioxa-8-aza-spiro[4.5]decane 
• 72152-31-9 7,7,9,9-tetramethyl-8-(3-phenyl-butyryl)-1,4-dioxa-8-aza-spiro[4.5]decane 
• 69961-52-0 7,7,9,9-tetramethyl-1,4-dioxa-8-aza-spiro[4.5]decane-8-carboxylic acid (4-hydroxy-4,4-diphenyl-but-1-en-c-yl)-methyl-amide 
• 69961-49-5 7,7,9,9-tetramethyl-1,4-dioxa-8-aza-spiro[4.5]decane-8-carboxylic acid (4-hydroxy-4-phenyl-but-1-en-c-yl)-methyl-amide 
• 69961-51-9 7,7,9,9-tetramethyl-1,4-dioxa-8-aza-spiro[4.5]decane-8-carboxylic acid [3-(1-hydroxy-cyclohexyl)-cis-propenyl]-methyl-amide 
• 72152-20-6 7,7,9,9-tetramethyl-8-(3-phenyl-acryloyl)-1,4-dioxa-8-aza-spiro[4.5]decane 

Relevant articles and documents

Ligand-Enabled Catalytic C-H Arylation of Aliphatic Amines by a Four-Membered-Ring Cyclopalladation Pathway

A palladium-catalyzed C-H arylation of aliphatic amines with arylboronic esters is described, proceeding through a four-membered-ring cyclopalladation pathway. Crucial to the successful outcome of this reaction is the action of an amino-acid-derived ligand. A range of hindered secondary amines and arylboronic esters are compatible with this process and the products of the arylation can be advanced to complex polycyclic molecules by sequential C-H activation reactions. Four corners: A palladium-catalyzed C-H arylation of aliphatic amines with arylboronic esters is described to proceed by a four-membered-ring cyclopalladation pathway. Crucial to the successful outcome of this reaction is the action of an amino-acid-derived ligand. A range of hindered secondary amines and arylboronic esters are compatible with this process and the products of the arylation can be advanced to complex polycyclic molecules by sequential C-H activation reactions.

Method for making piperidone ketals using polyphosphoric acid

A method for making piperidone ketals by condensing a suitable alcohol with a piperidone in the presence of polyphosphoric acid.