36796-54-0

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
(4-fluoro-phenyl)-(1-methyl-piperidin-4-yl)-amine is used as a potential candidate for the treatment of various neurological and psychiatric disorders due to its unique molecular structure and pharmacological properties. It is valuable for medicinal chemistry studies aimed at developing new drugs with improved efficacy and reduced side effects.

Upstream product

• 1445-73-4 1-Methyl-4-piperidone 
• 371-40-4 4-fluoroaniline 
• 36796-48-2 (4-fluoro-phenyl)-(1-methyl-piperidin-4-ylidene)-amine 

Downstream Products

• 202859-51-6 N-(4-fluorophenyl)-N-(piperidin-4-yl)propionamide 
• 117332-92-0 N-(4-Fluorophenyl)-N-<1-(2-phenylethyl)-4-piperidyl>propanamide Hydrochloride 
• 46960-72-9 N-(4-fluoro-phenyl)-N-(1-methyl-piperidin-4-yl)-propionamide 
• 96110-76-8 [4-Fluoro-2-(imino-phenyl-methyl)-phenyl]-(1-methyl-piperidin-4-yl)-amine 
• 786604-99-7 2-Chloro-1-[5-fluoro-2-(1-methyl-piperidin-4-ylamino)-phenyl]-ethanone 
• 93593-16-9 [5-Fluoro-2-(1-methyl-piperidin-4-ylamino)-phenyl]-(2-fluoro-phenyl)-methanone 
• 96110-84-8 {4-Fluoro-2-[(2-fluoro-phenyl)-imino-methyl]-phenyl}-(1-methyl-piperidin-4-yl)-amine 
• 96110-77-9 {2-[(2-Chloro-phenyl)-imino-methyl]-4-fluoro-phenyl}-(1-methyl-piperidin-4-yl)-amine 

Relevant academic research and scientific papers

Structure-activity studies of fentanyl

The preparation of analogues of fentanyl with para substituents in the anilino aromatic ring, anilino nitrogen separated from phenyl by methylene or bimethylene, and phenacyl replacing propionyl as the N-acyl substituent is reported. Although all para sub

Aminohaloborane in Organic Synthesis. IX. Exclusive ortho Acylation Reaction of N-Monoaminoalkylanilines

The exclusive ortho acylation reaction of aniline derivatives using boron trichloride made possible the one-step synthesis of 2-acyl-N-monoaminoalkylanilines (1) and the corresponding imines (2) from N-monoaminoalkylanilines, even in the case of compounds with a bulky substituent at the nitrogen atom.Conventional methods only give 1 via elaborate procedures.Keywords: regioselective reaction; 2-acylaniline derivative; 2-acylaniline-imine derivative; boron trichloride