367967-64-4

Basic information

• Product Name: methyl (S)-2-(benzyloxycarbonylamino)-3-(3-formyl-4-hydroxyphenyl)propionate
• Synonyms: methyl (S)-2-(benzyloxycarbonylamino)-3-(3-formyl-4-hydroxyphenyl)propionate
• CAS NO: 367967-64-4
• Molecular Weight: 357.363
• Mol File: 367967-64-4.mol

Chemical Properties

• CAS DataBase Reference: methyl (S)-2-(benzyloxycarbonylamino)-3-(3-formyl-4-hydroxyphenyl)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (S)-2-(benzyloxycarbonylamino)-3-(3-formyl-4-hydroxyphenyl)propionate(367967-64-4)
• EPA Substance Registry System: methyl (S)-2-(benzyloxycarbonylamino)-3-(3-formyl-4-hydroxyphenyl)propionate(367967-64-4)

Safety Data

• Hazardous Substances Data: 367967-64-4(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 79677-60-4 (S)-N-benzyloxycarbonyl-3-(4-hydroxy-3-iodophenyl)alanine methyl ester 
• 70-78-0 3-Iodo-L-tyrosine 
• 501-53-1 benzyl chloroformate 
• 79677-58-0 2-amino-3-(3-iodo-4-hydroxyphenyl)propionic acid methyl ester hydrochloride 
• 50-00-0 formaldehyd 
• 13512-31-7 N-(benzyloxycarbonyl)-L-tyrosine methyl ester 

Downstream Products

• 367967-66-6 N-[(phenylmethoxy)carbonyl]-3-formyl-O-(phenylmethyl)-L-tyrosine methyl ester 
• 1174157-79-9 methyl (S)-2-(benzyloxycarbonylamino)-3-[4-(diethoxyphosphoryloxy)-3-formylphenyl]propionate 
• 105229-41-2 N-[(phenylmethoxy)carbonyl]-3-hydroxy-O-(phenylmethyl)-L-tyrosine methyl ester 

Relevant articles and documents

A convenient preparation of selectively protected L-Dopa derivatives from 3-iodo-L-tyrosine

Palladium-catalyzed hydroformylation of 3-iodo-L-tyrosine derivatives la,b followed by protection of the free phenol as its benzyl ether and Baeyer-Villiger oxidation of the 3-formyl group provided the desired L-Dopa derivatives 4b,c in 71 and 68% overall

Synthesis and peptide incorporation of an unnatural amino acid containing activity-based probe for protein tyrosine phosphatases

An unnatural amino acid was synthesized to incorporate a quinone methide-generating activity-based probe for protein tyrosine phosphatases (PTPs) and then integrated into a PTP1B-specific substrate. The resulting probe led to preferential labeling of PTP1

Facile incorporation of a phosphatase activity-dependent quinone methide generating motif into phosphotyrosine

A novel phosphotyrosine analogue that incorporates a phosphatase activity-dependent quinone methide generating motif is synthesized from tyrosine. Following orthoformylation of the phenol moiety of methyl N-Cbz-tyrosinate, the Fmoc-protected 3-difluoromethyl analogue of phosphotyrosine is obtained by functional group transformations. Georg thieme Verlag Stuttgart.