36799-08-3Relevant academic research and scientific papers
Efficient synthesis of a new potential chelating agent for radioimmunotherapy
Gouin, Sébastien G.,Gestin, Jean-Fran?ois,Remaud, Patricia,Faivre-Chauvet, Alain,Meslin, Jean Claude,Deniaud, David
, p. 2080 - 2082 (2002)
The synthesis of a new rigid analogue of cyclohexyl-TTHA, an efficient lanthanide ligand, as well, as the first complexation trials are reported. This polyaminopolycarboxylic acid, Ph-DTHA 1, was obtained in five steps from phenylenediamine as starting pr
Synthesis and metal complexation properties of Ph-DTPA and Ph-TTHA: Novel radionuclide chelating agents for use in nuclear medicine
Gouin, Sebastien G.,Gestin, Jean-Francois,Monrandeau, Laurence,Segat-Dioury, Fabienne,Meslin, Jean Claude,Deniaud, David
, p. 454 - 461 (2007/10/03)
We wish to report the synthesis and metal complexation properties of new radionuclide chelating agents for use in nuclear medicine. The strategy includes the facile preparation of rigid analogues of DTPA and TTHA possessing an aromatic ring. The aromatic
