36804-17-8

Basic information

• Product Name: SILYBIN (MIXTURE OF SILYBIN A AND SILYBIN B)
• Synonyms: SILYBIN (MIXTURE OF SILYBIN A AND SILYBIN B);2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxine;Silibinin 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxine;(Mixture of Silybin A and Silybin B);Silybin
• CAS NO: 36804-17-8
• Molecular Formula: C₂₅H₂₂O₁₀
• Molecular Weight: 482.44
• Product Categories: Biochemistry;Flavonoids
• Mol File: 36804-17-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 160 °C
• Boiling Point: 793°C at 760 mmHg
• Flash Point: 274.4°C
• Appearance: /
• Density: 1.527g/cm³
• Vapor Pressure: 1.63E-26mmHg at 25°C
• Refractive Index: 1.684
• Storage Temp.: Freezer
• PKA: 7.39±0.60(Predicted)
• Merck: 14,8532
• CAS DataBase Reference: SILYBIN (MIXTURE OF SILYBIN A AND SILYBIN B)(CAS DataBase Reference)
• NIST Chemistry Reference: SILYBIN (MIXTURE OF SILYBIN A AND SILYBIN B)(36804-17-8)
• EPA Substance Registry System: SILYBIN (MIXTURE OF SILYBIN A AND SILYBIN B)(36804-17-8)

Safety Data

• RTECS: DJ2981770
• Hazardous Substances Data: 36804-17-8(Hazardous Substances Data)

Usage

General Description

Silybin, also known as silibinin, is a mixture of two diastereoisomers, silybin A and silybin B, derived from the milk thistle plant. It is a flavonolignan compound that has been found to have antioxidant, anti-inflammatory, and hepatoprotective properties. Silybin has been studied for its potential benefits in protecting the liver from damage caused by toxins, alcohol, and other substances. It is also being investigated for its potential anti-cancer effects and for its ability to improve skin health. Silybin is available as a dietary supplement and is commonly used in traditional medicine for liver disorders.

InChI:InChI=1/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20?,23-,24?,25+/m0/s1

Upstream product

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Relevant articles and documents

Total synthesis of (±)-silybin, an antihepatotoxic flavonolignan

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