3682-79-9

Usage

Structure

Heterocyclic compound with a benzo[d][1,2,3]triazole ring system and a bromophenyl substituent at the 2-position.

Physical state

Crystalline solid.

Usage

Commonly used in organic synthesis and medicinal chemistry as a building block for creating new compounds.

Potential properties

Studied for its potential anti-tumor and anti-inflammatory properties.

Fluorescent probe

Investigated as a fluorescent probe for detecting metal ions.

Material for organic light-emitting diodes

Explored as a material for organic light-emitting diodes.

Unique value

Its unique structure and versatility make it a valuable tool for researchers in various fields of chemistry.

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 586-78-7 para-nitrophenyl bromide 
• 88-74-4 2-nitro-aniline 
• 106-40-1 4-bromo-aniline 
• 612-29-3 o-nitronitrosobenzene 

Relevant academic research and scientific papers

Preparation method of 2-aryl benzotriazole compound

The invention relates to a synthesis method of a 2-aryl benzotriazole compound. In an organic solvent, under a nitrogen condition, an o-phenylenediamine compound with a structure shown as a formula (I) in the structural formula and an aryl nitrogen source with a structure shown as a formula (II) in the structural formula are used as reaction substrates to be successively subjected to intermolecular N-N coupling and intramolecular N-N bond coupling condensation by using a cheap copper-containing catalyst in a strong alkali environment so as to obtain a 2-aryl benzotriazole compound. According to the method, o-phenylenediamine and nitrobenzene raw materials are commercialized, cheap and easily available, the reaction substrate range is wide, the functional group tolerance is good, the reaction conditions are simple, the yield and purity of the product are high, a new synthesis route and a method are developed for the 2-aryl benzotriazole compound, and the method has good application potential and research value.

Cu(I)/KOH-Promoted Condensation between o-Arylenediamines and Nitroarenes to Access 2-Aryl-2H-Benzotriazoles

Reported is the condensation between o-arylenediamines and nitroarenes enabled by a cooperative action of acid and base, providing a direct entry to 2-aryl-2H-benzotriazoles. The potential practicability of this methodology was demonstrated by 100 mmol-scale reactions and the synthesis of serotonin/dopamine receptor ligand and human growth hormone. (Figure presented.).

Selective and Scalable Electrosynthesis of 2H-2-(Aryl)-benzo[d]-1,2,3-triazoles and Their N-Oxides by Using Leaded Bronze Cathodes

Electrosynthesis of 2H-2-(aryl)benzo[d]-1,2,3-triazoles and their N-oxides from 2-nitroazobenzene derivatives is reported. The electrolysis is conducted in a very simple undivided cell under constant current conditions with a leaded bronze cathode and a g