36824-00-7Relevant articles and documents
Rapid microwave-assisted synthesis of phenyl ethers under mildly basic and nonaqueous conditions
Sarju, Julien,Danks, Timothy N.,Wagner, Gabriele
, p. 7675 - 7677 (2004)
Microwave-assisted alkylation of phenols can be achieved within short reaction times under mild conditions using K2CO3 as a base, in methanol as a solvent. The method is suitable for base sensitive compounds or partially water-solubl
HETEROARYL INHIBITORS OF PAD4
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Paragraph 00328-00329, (2018/03/28)
The present invention provides compounds useful as inhibitors of PAD4, compositions thereof, and methods of treating PAD4-related disorders.
Homoserine lactone derivatives, preparation method thereof and pharmaceutical composition for prevention or treatment of the periodontal diseases containing the same as an active ingredient
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Paragraph 0242-0245, (2017/04/14)
The present invention relates to homoserine lactone derivatives, optical isomers of the same, or pharmaceutically acceptable salts of the same. The homoserine lactone derivatives in the present invention have excellent properties as a quorum sensing antagonist which hinders communications among bacteria. According to the present invention, the homoserine lactone derivatives can hinder gene expressions of bacteria while effectively blocking formation of biofilm which is known to raise resistance against antibiotics, and suppress propagation of bacteria, thereby being useful as a pharmaceutical composition for preventing or treating periodontal diseases.