36825-34-0

Usage

Uses

Used in Pharmaceutical Synthesis:
4-Bromo-3-quinolinamine is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs and medicinal compounds.
Used in Disease Treatment:
In the field of medicine, 4-Bromo-3-quinolinamine is used as a potential therapeutic agent for the treatment of various diseases, including cancer and infectious diseases, due to its interactions with biological systems.
Used in Antimicrobial Applications:
4-Bromo-3-quinolinamine is utilized as an antimicrobial agent, leveraging its properties to combat and control the growth of microorganisms, which is crucial in various medical and industrial settings.
Used in Antifungal Applications:
Similarly, in antifungal applications, 4-Bromo-3-quinolinamine serves to inhibit fungal growth, making it valuable in controlling fungal infections and contaminations in different environments.
The precise mechanisms of action of 4-Bromo-3-quinolinamine are still the subject of ongoing research, which may further expand its applications in the medical and pharmaceutical industries.

InChI:InChI=1/C9H7BrN2/c10-9-6-3-1-2-4-8(6)12-5-7(9)11/h1-5H,11H2

Upstream product

• 14213-02-6 3-azidoquinoline 
• 32112-94-0 4-quinolyl azide 
• 580-17-6 3-aminoquinoline 

Relevant academic research and scientific papers

Synthesis of N-Heterocycles-Fused Azasilines by Palladium-Catalyzed Si-Si Bond Activation

Azasilines fused nitrogen heterocycles are prepared in excellent yields (from 74 to 98 % according to the structures) for the first time in one operation with high regio- and stereoselectivities. The key step consists of an intramolecular palladium-cataly

INHIBITORS OF MALT1 AND USES THEREOF

Provided herein are compounds that inhibit MALTl, a protein whose activity is responsible for constitutive NF-κΒ signaling in certain cancers (e.g., activated B-cell diffuse large B-cell lymphoma (ABC-DLBCL)). Also provided are pharmaceutical compositions and kits comprising the compounds, and methods of treating MALTl -related diseases and disorders (e.g., cancer) with the compounds in a subject, by administering the compounds and/or compositions described herein.

PHOTOLYSIS OF PYRIDYL, QUINOLYL, AND ISOQUINOLYL AZIDES IN HYDROHALOGENOIC ACIDS

Photolysis of 4-azido-pyridine and -quinoline in hydrohalogenoic acids gave the 3-amino-4-halogeno compounds (2) via azirine or azacycloheptatetraene intermediates, whereas their N-oxides (4), under similar conditions, gave the 4-amino-3-halogeno compounds (5) presumably via nitrenium ion intermediates.In the 3-azidoquinoline and 4-azidoisoquinoline series, both free bases (6a, 8a) and N-oxides (6b, 8b) gave similar results to 4-azidopyridine and -quinoline N-oxides (4).