368425-40-5Relevant academic research and scientific papers
Synthesis of (E)-α,β-unsaturated amides with high selectivity by using samarium diiodide
Concellon, Jose M.,Perez-Andres, Juan A.,Rodriguez-Solla, Humberto
, p. 3062 - 3068 (2001)
Stereoselective β-elimination of 2-chloro-3-hydroxyamides 1 is achieved by using samarium diiodide to yield α,β-unsaturated amides 2, in which the C=C bond is di- tri-, or tetrasubstituted. The starting compounds 1 are easily prepared by reaction of the c
Sequential elimination-cyclopropanation reactions promoted by Samarium: Highly diastereoselective synthesis of cyclopropylamides
Concellon, Jose M.,Rodriguez-Solla, Humberto,Llavona, Ricardo
, p. 1132 - 1133 (2007/10/03)
trans-Cyclopropanamides were obtained, in high yield, from 2-chloro-3-hydroxyamides by a sequenced elimination-cyclopropanation process promoted by Samarium/ diiodomethane or Samarium diiodide and Samarium/ diiodomethane.
