368448-97-9Relevant academic research and scientific papers
In situ generation of N -Boc-protected alkenyl imines: Controlling the e / Z geometry of alkenyl moieties in the Mukaiyama-Mannich reaction
Bai, Jian-Fei,Sasagawa, Hajime,Yurino, Taiga,Kano, Taichi,Maruoka, Keiji
supporting information, p. 8203 - 8206 (2017/07/24)
Readily available Boc-protected Z-alkenyl aminals could be used as Z-alkenyl and E-alkenyl imine precursors under acidic conditions. In the Mukaiyama-Mannich reaction of Z-alkenyl Boc-aminals, the E/Z geometry of the products was controlled by the catalys
Serine-threonine protein phosphatase inhibitors derived from nodularin: Role of the 2-methyl and 3-diene groups in the Adda residue and the effect of macrocyclic conformational restraint
O'Donnell,Sanvoisin,Gani
, p. 1696 - 1708 (2007/10/03)
In order to probe the effect upon macrocycle conformation and PP1cat enzyme inhibition of structural changes to nodularin, specific replacements for the Adda residue were introduced. Two new analogues, cyclo[-(3S,E)-3-phenylethenyl-3-aminopropa
