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[(2-hydroxy-naphthalen-1-yl)-phenyl-methyl]-urea is a complex organic compound with the molecular formula C18H15N2O2. It is characterized by a naphthalene ring with a hydroxyl group at the 2-position, a phenyl ring attached to the naphthalene, and a methyl group connected to the phenyl ring. The urea functional group is formed by the carbonyl groups (C=O) and the amine group (NH2), which are linked to the phenyl ring. [(2-hydroxy-naphthalen-1-yl)-phenyl-methyl]-urea is known for its potential applications in the pharmaceutical industry, particularly as a building block for the synthesis of various drugs and medicinal compounds. Its structure allows for a range of chemical reactions and modifications, making it a versatile component in organic synthesis.

3686-36-0

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3686-36-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3686-36-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,8 and 6 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3686-36:
(6*3)+(5*6)+(4*8)+(3*6)+(2*3)+(1*6)=110
110 % 10 = 0
So 3686-36-0 is a valid CAS Registry Number.

3686-36-0Relevant academic research and scientific papers

Bovine bone-derived natural hydroxyapatite-supported ZnCl2 as a sustainable high efficiency heterogeneous biocatalyst for synthesizing amidoalkyl naphthols

Azzallou, Rachid,Geesi, Mohammed H.,Kaiba, Abdellah,Kamal, Mehnaz,Lazar, Sa?d,Mamouni, Rachid,Ouerghi, Oussama,Riadi, Yassine,Taleb, Mohamed Ait,Villain, Sylvie

, (2022/01/06)

Waste-derived materials have emerged as promising catalysts to meet the requirements for green chemistry. Catalysts and solvents are recognized as the most important components of the 12 principles of green chemistry. The reactivity of members of this cla

Cetrimonium bromide promoted efficient multi-component protocol for synthesis of 1-amidoalkyl-2-naphthols in aqueous medium

Nakhate,Ingale,Shinde

, p. 1620 - 1630 (2021/07/02)

An efficient and eco-friendly cetrimonium bromide promoted one-pot synthesis of 1-amidoalkyl-2-naphthols by the multicomponent condensation of aldehydes, β-naphthol and amides in water is reported. The wide range of substrate scope, excellent yield, short

Magnetite (Fe3O4) nanoparticles-supported dodecylbenzenesulfonic acid as a highly efficient and green heterogeneous catalyst for the synthesis of substituted quinolines and 1-amidoalkyl-2-naphthol derivatives

Katheriya, Deepak,Patel, Nipun,Dadhania, Harsh,Dadhania, Abhishek

, p. 805 - 816 (2020/10/02)

Abstract: Magnetically retrievable, magnetite (Fe3O4) nanoparticles-supported dodecylbenzenesulfonic acid (DDBSA@MNP) was synthesized and characterized through different analytical techniques such as TEM, XRD, FTIR, TGA, SEM, EDX and

Synthesis and characterization of pine-cone derived carbon-based solid acid: A green and recoverable catalyst for the synthesis of pyra-no_pyrazole, amino-benzochromene, amidoalkyl naphthol and thiazoli-dinedione derivatives

Ghorbani, Fatemeh,Pourmousavi, Seied Ali,Kiyani, Hamzeh

, p. 66 - 81 (2021/03/19)

In this report, SO3H-functionalized Carbon nanoparticles (Pine-SO3H) with high acid density have been synthesized by the thermal treatment of sulfuric acid with Pine-Cone as carbon-based at 180oC in a sealed autoclave in a

Solvent-free synthesis of 1-amidoalkyl-2-naphthols using magnetic nanoparticle-supported?2-(((4-(1-iminoethyl)phenyl)imino)methyl)phenol Cu (II) or Zn (II) Schiff base complexes

Ghorbani, Fatemeh,Kiyani, Hamzeh,Pourmousavi, Seied Ali,Ajloo, Davood

, p. 3145 - 3164 (2020/04/24)

Two magnetic nanoparticle-supported?2-(((4-(1-iminoethyl)phenyl)imino)methyl)phenols were successfully synthesized, characterized, and applied in the one-pot three-component reaction of substituted benzaldehydes, 2-naphthol, and amides for synthesis of 1-

Nanomagnetite-supported molybdenum oxide (nanocat-Fe-Mo): an efficient green catalyst for multicomponent synthesis of amidoalkyl naphthols

Bankar, Swapnil R.,Shelke, Sharad N.

, p. 3507 - 3521 (2018/02/21)

Abstract: Magnetite (Fe3O4)-supported molybdenum oxide (MoO3) was synthesized from simple starting precursors in aqueous medium. The synthesized nanocat-Fe-Mo was analyzed using several techniques such as X-ray diffraction

Characterization, Consideration and Catalytic Application of Novel Pyrazine-1,4-Diium Trifluoromethanesulfonate {[1,4-DHPyrazine](OTf)2} as a Green and Recyclable Ionic Liquid Catalyst in the Synthesis of Amidoalkyl Naphthol Derivatives

Alinezhad, Heshmatollah,Tajbakhsh, Mahmood,Norouzi, Mohammad

, p. 278 - 288 (2017/02/05)

An efficient and green one-pot method has been developed for the synthesis of amidoalkyl naphthol derivatives using reusable {[1,4-DHPyrazine](OTf)2} as an ionic liquid catalyst via condensation of aromatic aldehydes, β-naphthol and various ami

Sulfonated polynaphthalene as an effective and reusable catalyst for the one-pot preparation of amidoalkyl naphthols: DFT and spectroscopic studies

Pourmousavi, Seied Ali,Moghimi, Parvin,Ghorbani, Fatemeh,Zamani, Mehdi

, p. 87 - 102 (2017/05/15)

Sulfonated polynaphthalene (S-PNP) as a carbon-based solid acid efficiently catalyzed the one-pot three-component synthesis of amidoalkyl naphthols. The three-component process of substituted aryl aldehydes, 2-naphthol, and amide (benzamide and acetamide)

Nanocrystalline FeOCl:X grafted MCM-41 as active mesoporous catalyst for the solvent-free multi-condensation reaction

Dumbre, Deepa,Amin, Mohammad Hassan,Loh, Qing,Choudahry, Vasant R.,Selvakannan,Bhargava, Suresh K.

, p. 69334 - 69342 (2016/08/05)

Thermal condensation reaction between the surface silanol groups of MCM-41 and FeCl3 led to the formation of nanocrystalline iron oxychloride (FeOCl) grafted MCM-41 and its role as an active Lewis acid site for the solvent-free multi-condensation reaction has been demonstrated. TGA/TGA-FTIR-GC-MS analysis of the FeCl3/MCM-41 material showed the release of HCl molecules as a result of the condensation reaction and the formation of FeOClx species on the surface of MCM-41. Solid state Si29 NMR and HT-XRD analysis of these materials clearly showed the grafting of FeOClx species on the surface of MCM-41 and nanocrystalline FeOClx formation during the thermal condensation reaction. HRTEM mapping and EDX mapping further confirm the nanocrystalline iron oxychloride species formation and its uniform distribution on the surface of MCM-41. It was further demonstrated that these materials were found to be highly active towards solvent-free one pot multi condensation reaction between napthols, amides and aldehydes to produce pharmaceutically active alkylnapthols. The role of calcination temperature was demonstrated to be a key factor in the formation and distribution of FeOClx species, therefore the catalytic activity of these materials vary as a function of calcination temperature. XPS analysis of these materials confirmed the presence of FeOClx species and its role as an active acid site for the multi-condensation reaction was proposed.

Zirconocene dichloride catalyzed multi-component synthesis of 1-amidoalkyl-2-naphthols at ambient temperature

Khanapure, Sharanabasappa,Jagadale, Megha,Salunkhe, Rajashri,Rashinkar, Gajanan

, p. 2075 - 2085 (2016/03/16)

Zirconocene dichloride (Cp2ZrCl2) was found to be highly efficient catalyst for the synthesis of structurally diverse 1-amidoalkyl-2-naphthols by one-pot multi-component reaction (MCR) of 2-naphthol with a variety of aryl aldehydes a

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