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36884-17-0

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36884-17-0 Usage

General Description

"(3,4-Dihydro-2H-benzo[1,4]oxazin-3-yl)-methanol" is a chemical compound belonging to the category of benzoxazines. These are organic compounds that contain a benzene fused to an oxazine ring. Oxazine ring is a six-membered heterocyclic compound containing oxygen, nitrogen and four carbon atoms. Therefore, this chemical compound consists of a methanol substituent attached to the 3-position of the 2H-benzo[1,4]oxazin-3-one structure. This chemical is not known for any specific applications or industries it might be used in, and its physical and chemical properties are also not extensively reported or commentated on in scientific literature. Given its molecular structure, it is expected to display varied chemical reactions typical for compounds of its class.

Check Digit Verification of cas no

The CAS Registry Mumber 36884-17-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,8,8 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 36884-17:
(7*3)+(6*6)+(5*8)+(4*8)+(3*4)+(2*1)+(1*7)=150
150 % 10 = 0
So 36884-17-0 is a valid CAS Registry Number.

36884-17-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,4-dihydro-2H-1,4-benzoxazin-3-ylmethanol

1.2 Other means of identification

Product number -
Other names 2,3-dihydro-3-hydroxymethyl-1,4-benzoxazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:36884-17-0 SDS

36884-17-0Relevant articles and documents

Design, synthesis, and preliminary biological evaluation of 2,3-dihydro-3-hydroxymethyl-1,4-benzoxazine derivatives

Jiao, Pei-Fu,Zhao, Bao-Xiang,Wang, Wei-Wei,He, Qiu-Xia,Wan, Mao-Sheng,Shin, Dong-Soo,Miao, Jun-Ying

, p. 2862 - 2867 (2006)

We synthesized a series of novel small molecules, 2,3-dihydro-3-hydroxymethyl-1,4-benzoxazine derivatives, by tandem reduction-oxirane opening of 2-nitroaroxymethyloxiranes in moderate or excellent yields. We investigated the effects of all of the compounds on HUVEC apoptosis and A549 cell growth. The results showed that 6,8-dichloro-2,3-dihydro-3-hydroxymethyl-1,4-benzoxazine was the most effective small molecule in promoting HUVEC apoptosis and inhibiting A549 cell proliferation, but 6-amino-2,3-dihydro-3-hydroxymethyl-1,4-benzoxazine could remarkably inhibit HUVEC apoptosis and might induce the formation of microvessel.

Transition-Metal Acetate-Promoted Intramolecular Nitrene Insertion to Vinylogous Carbonates for Divergent Synthesis of Azirinobenzoxazoles and Benzoxazines

Gharpure, Santosh J.,Naveen, Sudi,Samala, Ganesh,Vishwakarma, Dharmendra S.

, p. 1456 - 1460 (2019/01/04)

Synthesis and isolation of highly unstable azirinobenzoxazole and benzoxazines in a chemodivergent fashion from aryl azido vinylogous carbonates by simple change in transition metal acetate is described. Thermal or rhodium(II) acetate-mediated decompositi

First use of HEH in oxazine synthesis: Hydroxy-substituted 2 H-1,4-benzoxazine derivatives

Meng, Qing-Yuan,Liu, Qiang,Li, Jing,Xing, Rui-Guang,Shen, Xiao-Xia,Zhou, Bo

experimental part, p. 3283 - 3286 (2010/03/04)

The synthesis of 2H-1,4-benzoxazine derivatives from 1,2-epoxy-3-(2- nitroaryloxy)propanes in the presence of Hantzsch 1,4-dihydropyridine (HEH) and Pd/C as a catalyst was achieved. The nitro group was reduced before the epoxide functionality, leading to attack of the amino group on the epoxide moiety in a 6-exo-fashion. By introducing a methyl group at the 1-position, the 7-endo ring-closed product could also be formed. Georg Thieme Verlag Stuttgart - New York.

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