368861-72-7Relevant academic research and scientific papers
Organic luminescent material based on 1, 6-naphthyridine receptor structural unit and application thereof
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Paragraph 0054; 0055; 0057, (2021/01/12)
The invention discloses an organic luminescent material containing a 1, 6-naphthyridine receptor structural unit as shown in a formula (1) and application of the organic luminescent material. According to the organic luminescent material, the electrophilic 1, 6-naphthyridine structural unit is taken as a receptor, different donors are combined, a thermally induced delayed fluorescence material with high quantum efficiency, easily adjustable light-emitting color and good thermal stability can be formed, and can be used for preparing a dark blue light-emitting device and has a huge application prospect in the field of OLED materials.
Synthesis of 3-substituted 4-aroylisoquinolines via Pd-catalyzed carbonylative cyclization of 2-(1-alkynyl)benzaldimines
Dai, Guangxiu,Larock, Richard C.
, p. 7042 - 7047 (2007/10/03)
A number of 3-substituted 4-aroylisoquinolines have been prepared in good yields by treating N-tert-butyl-2-(1-alkynyl)benzaldimines with aryl halides in the presence of CO and a palladium catalyst. Synthetically the methodology provides a simple and convenient route to isoquinolines containing an aryl, alkyl, or vinylic group at C-3 and an aroyl group at C-4 of the isoquinoline ring. The reaction is believed to proceed via cyclization of the alkyne containing a proximate nucleophilic center promoted by an acylpalladium complex.
Synthesis of isoquinolines and pyridines by the palladium/copper-catalyzed coupling and cyclization of terminal acetylenes and unsaturated imines: The total synthesis of decumbenine B
Roesch, Kevin R.,Larock, Richard C.
, p. 86 - 94 (2007/10/03)
Monosubstituted isoquinolines and pyridines have been prepared in good to excellent yields via coupling of terminal acetylenes with the tert-butylimines of o-iodobenzaldehydes and 3-halo-2-alkenals in the presence of a palladium catalyst and subsequent copper-catalyzed cyclization of the intermediate iminoalkynes. In addition, isoquinoline heterocycles have been prepared in excellent yields via copper-catalyzed cyclization of iminoalkynes. The choice of cyclization conditions is dependent upon the nature of the terminal acetylene that is employed, as only aryl and alkenyl acetylenes cyclize under the palladium-catalyzed reaction conditions that have been developed. However, aryl-, vinylic-, and alkyl-substituted acetylenes undergo palladium-catalyzed coupling and subsequent copper-catalyzed cyclization in excellent yields. The total synthesis of the isoquinoline natural product decumbenine B has been accomplished in seven steps and 20% overall yield by employing this palladium-catalyzed coupling and cyclization methodology.
