369-30-2

Usage

Chemical Properties

pale yellow crystalline solid

InChI:InChI=1/C9H9FO3/c1-12-8-4-3-6(5-7(8)10)9(11)13-2/h3-5H,1-2H3

Upstream product

• 121-98-2 methyl 4-methoxybenzoate 
• 350-29-8 3-fluoro-4-hydroxybenzoic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 403-20-3 3-fluoro-p-anisic acid 
• 898786-96-4 C₁₀H₈FNO₂ 
• 329-46-4 3-amino-5-fluoro-4-methoxy-benzoic acid methyl ester 
• 455-76-5 N-benzenesulfonyl-N'-(3-fluoro-4-methoxy-benzoyl)-hydrazine 
• 351-52-0 3-fluoro-4-methoxybenzyl chloride 
• 96047-32-4 3-fluoro-4-methoxybenzyl alcohol 
• 364-28-3 3-fluoro-4-methoxy-5-nitro-benzoic acid methyl ester 
• 403-10-1 3-fluoro-4-methoxybenzohydrazide 

Relevant academic research and scientific papers

TROPANE COMPOUNDS

A compound according to Formula I or II: (I) or (II) wherein R1, R1b, R2, L1, and L2 and L2b are as defined in the specification, pharmaceutical compositions thereof, and methods of use thereof.

Elemental fluorine Part 12. Fluorination of 1,4-disubstituted aromatic compounds

Direct fluorination of a series of 1,4-disubstituted benzene derivatives in acid reaction media at convenient temperature leads, in many cases, to selectively fluorinated aromatic products in preparatively useful conversions and yields.

Fluorination process

According to the present invention there is provided a process for the selective introduction of one or more fluorine atoms into a disubstituted aromatic compound in an acid medium with fluorine gas characterized in that the acid medium has a dielectric constant of at least 20 and a pH of less than 3. The present process provides a cost effective means of selectively introducing one or more fluorine atoms into an aromatic compound in good overall yield.