36930-63-9 Usage
Description
1,5-I-AEDANS, also known as an aminonaphthalenesulfonic acid fluorophore, is a chemical compound with a structure consisting of ethylenediamine substituted on the nitrogens with iodoacetyl and 5-sulfonyl-1-naphthyl groups. It is a yellow powder that exhibits fluorescence properties, with a maximum absorption wavelength of 336 nm and a maximum emission wavelength of 490 nm. Due to its reactivity with thiol compounds and sulfhydryl groups, it is widely used as a fluorescent sulfhydryl reagent.
Uses
Used in Biochemical Research:
1,5-I-AEDANS is used as a fluorescent sulfhydryl reagent for biochemical research, particularly in the detection and analysis of thiol compounds and sulfhydryl groups. Its sensitivity to photo-catalyzed degradation in both aqueous solutions and organic solvents makes it a valuable tool for studying protein-protein interactions, enzyme activity, and other biological processes involving thiol groups.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,5-I-AEDANS is used as a labeling agent for the detection and quantification of thiol-containing drugs and drug candidates. Its fluorescence properties allow for the easy tracking and monitoring of these compounds during drug development and testing processes.
Used in Environmental Science:
1,5-I-AEDANS is employed as a sensitive and selective probe for the detection of mercury ions in environmental samples. Its reactivity with mercury ions results in a significant enhancement of its fluorescence signal, making it a useful tool for monitoring mercury contamination in water, soil, and air samples.
Used in Material Science:
In material science, 1,5-I-AEDANS is utilized as a fluorescence-based sensor for the detection of various analytes, such as metal ions, anions, and small organic molecules. Its ability to form covalent derivatives with thiol-containing materials makes it a versatile probe for the development of novel sensing materials and devices.
Used in Analytical Chemistry:
1,5-I-AEDANS is used as a derivatization agent in analytical chemistry for the detection and quantification of thiol-containing compounds in complex samples. Its fluorescence properties enable sensitive and selective detection of these compounds, making it a valuable tool for the analysis of biological, environmental, and industrial samples.
Check Digit Verification of cas no
The CAS Registry Mumber 36930-63-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,9,3 and 0 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 36930-63:
(7*3)+(6*6)+(5*9)+(4*3)+(3*0)+(2*6)+(1*3)=129
129 % 10 = 9
So 36930-63-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H15IN2O4S/c15-9-14(18)17-8-7-16-12-5-1-4-11-10(12)3-2-6-13(11)22(19,20)21/h1-6,16H,7-9H2,(H,17,18)(H,19,20,21)
