75585-80-7

Basic information

• Product Name: testosterone-cysteamine-DANS
• Synonyms: testosterone-cysteamine-DANS
• CAS NO: 75585-80-7
• Molecular Formula: C37H50N4O7S2
• Molecular Weight: 726.9455
• Mol File: 75585-80-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.415g/cm³
• Refractive Index: 1.675
• CAS DataBase Reference: testosterone-cysteamine-DANS(CAS DataBase Reference)
• NIST Chemistry Reference: testosterone-cysteamine-DANS(75585-80-7)
• EPA Substance Registry System: testosterone-cysteamine-DANS(75585-80-7)

Safety Data

• Hazardous Substances Data: 75585-80-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C37H50N4O7S2/c1-36-15-13-25(21-24(36)9-10-28-29-11-12-33(42)37(29,2)16-14-30(28)36)41-48-22-34(43)40-19-20-49-23-35(44)39-18-17-38-31-7-3-6-27-26(31)5-4-8-32(27)50(45,46)47/h3-8,21,28-30,33,38,42H,9-20,22-23H2,1-2H3,(H,39,44)(H,40,43)(H,45,46,47)/b41-25-/t28?,29?,30?,33-,36-,37-/m0/s1

Upstream product

• 58116-37-3 (Z)-testosterone 3-(O-carboxymethyl)oxime 
• 36930-63-9 5-((((2-iodoacetyl)amino)ethyl)amino)-naphthalene-1-sulfonic acid 
• 156-57-0 2-mercaptoethylamine hydrochloride 

Relevant articles and documents

The preparation of three fluorescence-labelled derivatives of testosterone

Three fluorescence-labelled derivatives of testosterone were prepared consisting of the steroid separated from the fluorochrome by a hydrocarbon 'bridge'. 'Bridges' of different lengths (C2 to C7) were used as the length required to avoid steric hindrance effects by the fluorochrome in studies on steroid-protein binding was unknown. The three derivatives prepared were: 17β-hydroxy-4-androsten-3-one 3-(O-(N-(2'-mercapto)ethyl)carbamoylmethyl)oxime, 17β-hydroxy-4-androsten-3-one 3-(o-(N-(3'-amino)propyl)carbamoylmethyl)oxime and 17β-hydroxy-4-androsten-3-one 3-(O-(N-(7'-amino)heptyl)carbamoylmethyl)oxime. These were then coupled with either a dansyl or a fluorescein molecule. Overall yields were sufficient and the products immunoreactive with anti-testosterone antiserum.