36935-88-3Relevant academic research and scientific papers
Carbonylative synthesis of phthalimides and benzoxazinones by using phenyl formate as a carbon monoxide source
Chavan, Sujit P.,Bhanage, Bhalchandra M.
, p. 2405 - 2410 (2015/04/22)
A simple and efficient palladium-catalyzed carbonylative cyclization of N-substituted 2-iodobenzamides and 2-iodoanilides was investigated for the synthesis of phthalimides and benzoxazinones, respectively, by using phenyl formate as a CO source. The present catalytic protocol circumvents the use of an expensive phosphine ligand as well as solvent in the case of the phthalimide synthesis. Moreover, mild reaction conditions and a tolerance of various functional groups enhance the general applicability of this method.
Efficient palladium-catalyzed double carbonylation of o-dibromobenzenes: Synthesis of thalidomide
Chen, Jianbin,Natte, Kishore,Spannenberg, Anke,Neumann, Helfried,Beller, Matthias,Wu, Xiao-Feng
supporting information, p. 5578 - 5581 (2014/07/22)
We describe here a convenient and mild procedure for double carbonylation of o-dibromobenzenes with various 2-amino pyridines and naturally occurring amines, thus providing in good to excellent yields N-substituted phthalimides by using this palladium-catalyzed carbonylation procedure. Furthermore, for the first time we have applied the developed synthetic protocol for the synthesis of biologically active molecule thalidomide via a single step carbonylative cyclization reaction in excellent yield. the Partner Organisations 2014.
Use of pyridyl phthalimides as plant growth regulants
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, (2008/06/13)
Certain pyridyl phthalimides have been found to be effective in regulating the growth of leguminous plants.
Substituted phthalimides for regulating the growth of plants
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, (2008/06/13)
Certain substituted phthalimides have been found to be effective in regulating the growth of corn plants.
