369376-68-1Relevant articles and documents
Efficient entry to 1-benzoxepine ring skeleton via tandem SN2/Wittig reaction. Total synthesis of NADH: Ubiquinone oxidoreductase (complex I) antagonist pterulinic acid
Lin, Yuh-Lin,Kuo, Hsien-Shou,Wang, Yi-Wen,Huang, Sheng-Tung
, p. 1277 - 1281 (2003)
Concise synthesis of NADH: ubiquinone oxidoreductase (complex I) antagonist pterulinic acid (1a) is reported. The key architectural framework in the natural product, 1-benzoxepine ring skeleton, was smoothly prepared from known salicylaldehyde 2g and phos
Gold-catalyzed tandem intramolecular heterocyclization/petasis-ferrier rearrangement of 2-(Prop-2-ynyloxy)benzaldehydes as an expedient route to benzo[b]oxepin-3(2a H)-ones
Sze, Ella Min Ling,Rao, Weidong,Koh, Ming Joo,Chan, Philip Wai Hong
, p. 1437 - 1441 (2011/04/15)
The golden ring: A synthetic approach to benzo[b]oxepin-3(2a H)-ones by heterocyclization/Petasis-Ferrier rearrangement of 2-(prop-2-ynyloxy) benzaldehydes is reported. Uniquely, the ring formation was found to only proceed efficiently in the presence of
Construction of medium-ring oxacycloalkenones. Extension towards benzo-fused cyclic ethers
Lecornue, Frederic,Ollivier, Jean
, p. 3600 - 3604 (2007/10/03)
A study was done on the construction of medium-ring oxacycloalkenones. The synthetic protocol consisted of the intramolecular Kulinlovich cyclopropanation on oxa-esters bearing a terminal double bond, followed by oxidative cleavage of the cyclopropanol mo
