36946-77-7

Upstream product

• 556-90-1 pseudothiohydantoin 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 556-90-1 pseudothiohydantoin 

Downstream Products

• 57593-68-7 6-benzylidene-2-(4-dimethylamino-benzylidene)-6H-imidazo[2,1-b]thiazole-3,5-dione 
• 57518-52-2 2-(4-dimethylamino-benzylidene)-6H-imidazo[2,1-b]thiazole-3,5-dione 
• 129650-73-3 5-amino-2-(4-dimethylaminobenzylidene)-7-iminothiazolo<3,2-a>pyrimidin-3-one 

Relevant academic research and scientific papers

A facile synthesis of 5-arylidene-2-imino-4-thiazolidinones under microwave irradiation

A series of 5-arylidene-2-imino-4-thiazolidinone derivatives were synthesized by the cross-aldol condensation of aromatic aldehydes with 2-imino-4-thiazolidinone in sodium acetate/acetic acid under microwave irradiation. The reactions were completed in 10 min with 63-91% yields, were environmental benign, and had easy workup. Copyright Taylor & Francis Group, LLC.

Heterophase N-aminomethylation of 5-arylidenepseudothiohydantoins by arylamines and aqueous formaldehyde in aromatic solvents: Effect of substituents in the heterocyclic substrate and the aryl amine on the efficiency of the process

We have obtained a series of 3-aryl-7-arylidene-3,4-dihydro-2H-[1,3] thiazolo[3,2-a][1,3,5]triazin-6(7H)-ones by means of heterophase aminomethylation of 2-amino-5-arylidene-1,3-thiazol-4(5H)-ones with aqueous formaldehyde and aromatic amines in benzene or toluene. We explain the effect of substituents in the heterocyclic substrate and the aryl amine on the efficiency of the process within a detailed scheme for one of the possible aminomethylation reaction routes.