36952-40-6Relevant academic research and scientific papers
Copper-Catalyzed Asymmetric Arylation of N-Heteroaryl Aldimines: Elementary Step of a 1,4-Insertion
Wu, Chunlin,Qin, Xurong,Moeljadi, Adhitya Mangala Putra,Hirao, Hajime,Zhou, Jianrong Steve
supporting information, p. 2705 - 2709 (2019/02/06)
Copper complexes of monodentate phosphoramidites efficiently promote asymmetric arylation of N-azaaryl aldimines with arylboroxines. DFT calculations and experiments support an elementary step of 1,4-insertion in the reaction pathway, a step in which an aryl-copper species adds directly across four atoms of C=N?C=N in the N-azaaryl aldimines.
Synthesis of N-benzylated-2-aminoquinolines as ligands for the Tec SH3 domain
Inglis, Steven R.,Jones, Rhiannon K.,Booker, Grant W.,Pyke, Simon M.
, p. 387 - 390 (2007/10/03)
In recent work, we have been developing 2-aminoquinolines as ligands for Src Homology 3 (SH3) domains, so far the only reported examples of small-molecule ligands for these domains. In this paper, we report the synthesis of a series of N-benzylated-2-amin
