369656-66-6

Upstream product

• 369656-38-2 4-{[(tert-butoxycarbonyl)(1H-imidazol-2-ylmethyl)amino]methyl}benzoic acid 
• 369656-65-5 N-[(1S)-1-(1-naphthyl)ethyl]-5-phthalimide-(S)-2-(Boc-amino)pentanoylamide 

Downstream Products

• 369656-67-7 N-[(1S)-1-(1-naphthyl)ethyl]-5-amino-(S)-2-[4-[N-Boc-N-(imidazol-2-ylmethyl)aminomethyl]benzoyl]aminopentanoylamide 

Relevant academic research and scientific papers

CXCR4-ANTAGONISTIC DRUGS COMPRISING NITROGEN-CONTAINING COMPOUND

To provide novel nitrogen-containing compounds having antagonism to CXCR4 and remedies for disease, such as rheumatism, cancer metastasis, etc., based on the CXCR4 antagonism. Nitrogen-containing compounds represented by the following general formula and

NOVEL NITROGENOUS COMPOUND AND USE THEREOF

A novel nitrogen-containing compound effective against diseases such as HIV viral infectious diseases, rheumatism, and cancerous metastasis. It is a nitrogen-containing compound represented by the following general formula (1). In the formula, A typically represents a group represented by the formula (2) (A1 is hydrogen or an optionally substituted, mono- or polycyclic, heteroaromatic or aromatic ring; G1 is a single bond or a hydrocarbon group represented by the following formula (3) wherein R1, R2, and R3 may be optionally substituted hydrocarbon groups); W is an optionally substituted hydrocarbon group or heterocyclic ring; x is -C(=O)NH-; y is -C(=O)-; and D1 is hydrogen atom, alkyl having a polycyclic aromatic ring, di (substituted alkyl)amine, or alicyclic amine.