369656-75-7 Usage
Uses
Used in Biochemical Research:
URIDINE-2-13C, 1,3-15N2 is used as a labeled compound for studying the metabolism and incorporation of Uridine in biological systems. The stable isotopes in the molecule enable researchers to track and analyze the metabolic pathways and interactions involving Uridine.
Used in Pharmaceutical Industry:
URIDINE-2-13C, 1,3-15N2 is used as a labeled reference material for the development and validation of analytical methods in the pharmaceutical industry. The stable isotope labeling allows for accurate quantification and identification of Uridine in drug formulations and biological samples.
Used in Diagnostic Applications:
In the field of diagnostics, URIDINE-2-13C, 1,3-15N2 can be used as a labeled tracer to study the uptake and utilization of Uridine in various diseases and conditions. This can help in understanding the role of Uridine in disease progression and the development of targeted therapies.
Used in Nutritional Studies:
URIDINE-2-13C, 1,3-15N2 can be employed as a labeled nutrient in nutritional studies to investigate the role of Uridine in cellular metabolism, energy production, and overall health. The stable isotope labeling allows for the assessment of Uridine's bioavailability and its impact on various physiological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 369656-75-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,9,6,5 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 369656-75:
(8*3)+(7*6)+(6*9)+(5*6)+(4*5)+(3*6)+(2*7)+(1*5)=207
207 % 10 = 7
So 369656-75-7 is a valid CAS Registry Number.
369656-75-7Relevant academic research and scientific papers
Hatano, Akihiko,Shiraishi, Mitsuya,Terado, Nanae,Tanabe, Atsuhiro,Fukuda, Kenji
, p. 6683 - 6688 (2015)
Thymidine phosphorylase was used to catalyze the conversion of thymidine (or methyluridine) and uracil incorporating stable isotopes to deoxyuridine (or uridine) with the uracil base incorporating the stable isotope. These base-exchange reactions proceede
Synthetic method of double-labeled uridine-(C,N2)
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Paragraph 0013; 0023; 0027-0028; 0032-0033; 0037-0038, (2017/08/27)
The invention relates to a synthetic method of double-labeled uridine-(C,N2). The method comprises the following steps: carrying out a cyclization reaction on double-labeled urea-(C,N2) and propiolic acid in a solvent anhydrous benzene to obtain double-labeled uracil-(C,N2); and mixing the double-labeled uracil-(C,N2) with 1-acetoxy-2,3,5-tribenzoyloxy-beta-D-ribofuranose in a solvent acetonitrile in Ar2 atmosphere, adding hexamethyldisilazane and trimethylsilyl trifluoromethanesulfonate, post-processing above materials to obtain an intermediate, and hydrolyzing the intermediate with ammonia water to obtain the double-labeled uridine-(C,N2). Compared with the prior art, the method disclosed in the invention has the advantages of simple process, high yield, no decrease of the isotope abundance, and suitableness for laboratory production of the double-labeled uridine-(C,N2).
