36980-95-7

Upstream product

• 6214-65-9 5-acetyluracil 
• 74-88-4 methyl iodide 
• 186581-53-3 diazomethane 
• 4869-46-9 1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidine-5-carbaldehyde 

Downstream Products

• 74816-66-3 2'-Methoxy-2,4-dioxo-1,3-dimethyl-6'-phenyl-1,2,3,4-tetrahydro-4',5-dipyrimidinyl 
• 74816-68-5 2'-Chloro-2,4-dioxo-1,3-dimethyl-6'-phenyl-1,2,3,4-tetrahydro-4',5-dipyrimidinyl 
• 74816-70-9 2,2',4-Trioxo-1,3,3'-trimethyl-6'-phenyl-1,2,2',3,3',4-hexahydro-4',5-dipyrimidinyl 
• 74816-67-4 2,2',4-Trioxo-1,3-dimethyl-6'-phenyl-1,1',2,2',3,4-hexahydro-4',5-dipyrimidinyl 
• 96-31-1 N,N'-Dimethylurea 
• 74115-56-3 6-Acetyl-1,3-dimethyl-1H,8H-pyrido[2,3-d]pyrimidine-2,4,7-trione 

Relevant academic research and scientific papers

Researches on antiviral agents. 3. Synthesis and transformations of racemic and chiral 6-oxiranyl pyrimidinones

The synthesis of epoxides 3, 4 and 6 has been described. The transformation of 3 into C-6 alkylated uracils 22a-e, 23a-d, 24 and 25 is also reported. The chiral epoxide (S)-(+)-3 has been prepared via a modified Solladie procedure, while the ZnCl2- DIBAH reduction step failed to give the expected enantiomer (R)-(-)-3. This result has been discussed on the ground of molecular modeling studies.

PYRIMIDINES. 71. REARRANGEMENTS OF 2,2',4-TRIMETHOXY-6'-PHENYL-4',5-DIPYRIMIDINYL TO N-METHYL OXO DERIVATIVES

A trimethoxy derivative with three nonequivalent methoxy groups was obtained from 2,2',4-trichloro-6'-phenyl-4',5-dipyrimidinyl.Rearrangement of 2,2',4-trimethoxy-6'-phenyl-4',5-dipyrimidinyl under Hilbert-Johnson conditions and thermal rearrangement with