3700-59-2

Usage

Uses

Used in Paints and Coatings Industry:
Santomerse DT is used as a defoamer and air release agent for improving the production process and product quality in paints and coatings. It helps in reducing foam and enhancing the flow of the paint, leading to a smoother application and better finish.
Used in Adhesives Industry:
In the adhesives industry, Santomerse DT is used as a defoaming agent to prevent air entrapment and ensure a consistent adhesive application. Its ability to reduce surface tension allows for improved adhesive flow and bonding performance.
Used in Water-Based Systems:
Santomerse DT is used as a defoamer and air release agent in water-based systems across various industries. Its effectiveness in preventing or eliminating foam formation contributes to improved production processes and product quality, making it a valuable additive for a wide range of formulations.

Upstream product

• 143-15-7 1-dodecylbromide 
• 111-40-0 3-azapentane-1,5-diamine 
• 112-52-7 1-chlorododecane 
• 4292-19-7 1-Iodododecane 

Downstream Products

• 6843-97-6 dodicin 

Relevant academic research and scientific papers

Synthesis of a novel lipophilic gadolinium complex as a potential MRI contrast agent

The synthesis of a novel lipophilic diethylentriaminotetracetic(DTTA)- dodecane gadolinium complex is reported. The Gd-DTTA-dodecane complex is able to form mixed micelles with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and a non-ionic surfactant like Tween 80. This novel multicomponent system can find potential application in magnetic resonance angiography (MRA). Georg Thieme Verlag Stuttgart.

STERILE/ANTIBACTERIAL COMPOSITION

DISCLOSED IS A STERILE/ANTIBACTERIAL COMPOSITION, A LIQUID DETERGENT COMPOSITION OR A COMPOSITION FOR TREATING A FIBER PRODUCT, WHICH COMPRISES A MIXTURE OF COMPONENTS (A1) AND (B1) OR A COMPLEX FORMED BY THE COMPONENTS (A1) AND (B1), WHEREIN THE COMPONENT (A1) IS A WATER-SOLUBLE SILVER SALT, A WATER-SOLUBLE COPPER SALT OR A WATER-SOLUBLE ZINC SALT AND THE COMPONENT (B1) IS AT LEAST ONE LONG-CHAIN ALKYLAMINE COMPOUND SELECTED FROM A COMPOUND REPRESENTED BY GENERAL FORMULA (I) AND A COMPOUND REPRESENTED BY GENERAL FORMULA (II) AND/OR AN ANION PRODUCED FROM THE LONG-CHAIN ALKYLAMINE COMPOUND. IN FORMULA (I), R1 REPRESENTS AN ALKYL GROUP HAVING 8 TO 22 CARBON ATOMS; A1 REPRESENTS A HYDROGEN ATOM OR (CH?)m,-COOX2; X1 AND X2 INDEPENDENTLY REPRESENT A HYDROGEN ATOM, AN ALKALI METAL ATOM, AN ALKALI EARTH METAL ATOM, OR A CATIONIC AMMONIUM GROUP; N REPRESENTS A NUMBER OF 1 TO 3; AND M REPRESENTS A NUMBER OF 1 TO 3. IN FORMULA (II), R2 REPRESENTS AN ALKYL OR ACYL GROUP HAVING 8 TO 22 CARBON ATOMS; Q REPRESENTS (NH-(CH?)m); R REPRESENTS A NUMBER OF 1 OR 0, PROVIDED THAT A2 AND A3 INDEPENDENTLY REPRESENT A HYDROGEN ATOM OR A METHYL GROUP WHEN R REPRESENTS 0, AND A2 REPRESENTS A HYDROGEN ATOM AND A3 REPRESENTS A HYDROGEN ATOM OR CH?COOX3 WHEN R REPRESENTS 1; X3 REPRESENTS A HYDROGEN ATOM, AN ALKALI METAL ATOM, AN ALKALI EARTH METAL ATOM OR A CATIONIC AMMONIUM GROUP; N REPRESENTS A NUMBER OF 1 TO 3; AND M REPRESENTS A NUMBER OF 1 TO 3.

Combinatorial synthesis and high-throughput screening of alkyl amines for nonviral gene delivery

Efficient delivery of plasmid DNA and siRNA into cells is essential for biological and biomedical research. Although significant efforts have been made to develop efficient nonviral vectors, such as cationic lipids and polymers, most of the vectors require multistep synthesis, which complicates both fast structural optimizations and combinatorial synthesis of such vectors. Here, we present a facile, single-step method based on an alkylation of amines, allowing for the fast parallel synthesis of libraries of cationic lipid-like molecules (lipidoids). We exploited the method to synthesize 200 lipidoids, which were screened for their transfection efficiency in HEK293T cells. The screen resulted in about 2% of new lipidoids capable of efficient cell transfection similar or higher than the efficiency of Lipofectamine 2000. In addition, we observed an enhancement of cellular transfection by combining single- with double-chain lipidoids, which was attributed to the different roles of the single- and double-tailed lipids in the mixed liposomes.