37006-34-1

Upstream product

• 68588-31-8 5-[(1H-indol-3-yl)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 253191-72-9 1-pivaloyl-4-bromo-5-oxo-1,3,4,5-tetrahydrobenz[c,d]indole 
• 56-23-5 tetrachloromethane 
• 3744-82-9 3,4-dihydrobenzo[cd]indol-5(1H)-one 
• 95-50-1 1,2-dichloro-benzene 
• 119-64-2 tetralin 
• 408312-44-7 1,2-dihydro-benz[cd]indol-5-ol 
• 160320-10-5 1-(2,2-Dimethyl-propionyl)-3,4-dihydro-1H-benzo[cd]indol-5-one 

Relevant academic research and scientific papers

Chemistry of Indoles Carrying a Basic Function. Part V. Some Observations while Constructing the Ergoline Ring by the Stobbe Reaction

Starting from the N-pivaloyl derivative of Uhle's ketone (6), amide 11 was prepared with a succinic diester side chain. Under the conditions of Stobbe condensation imide 12 was formed rather than the expected intermediate containing an ergoline ring.

Flash Vacuum Pyrolysis of 5-(Indol-2- and -3-ylmethylene)-2,2-dimethyl-1,3-dioxane-4,6-diones

Flash vacuum pyrolysis of 5-(indol-2- and -3-ylmethylene)-2,2-dimethyl-1,3-dioxane-4,6-diones results in the initial formation of indolylmethyleneketenes, which generally either lose carbon monoxide to produce ethynylindoles or undergo -sigmatropic shifts, followed by electrocyclic rearrangements, to yield carbazolols or benzindol-5(1H)-one. 5-(Indol-2-ylmethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione and the 3-methylindol-2-yl derivative both yield 3H-pyrroloindol-3-ones via a -sigmatropic rearrangement of the initially formed ketene.