37021-63-9

Basic information

• Product Name: 2-Nitro-4-benzylphenol
• Synonyms: 2-Nitro-4-benzylphenol
• CAS NO: 37021-63-9
• Molecular Formula: C₁₃H₁₁NO₃
• Molecular Weight: 0
• Mol File: 37021-63-9.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Nitro-4-benzylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Nitro-4-benzylphenol(37021-63-9)
• EPA Substance Registry System: 2-Nitro-4-benzylphenol(37021-63-9)

Safety Data

• Hazardous Substances Data: 37021-63-9(Hazardous Substances Data)

Upstream product

• 101-53-1 p-benzylphenol 
• 4560-41-2 2-benzyloxynitrobenzene 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 

Downstream Products

• 4097-57-8 3.5-dinitro-4-oxy-diphenylmethane 
• 317334-89-7 4-benzyl-2-bromo-6-nitro-phenol 
• 27618-10-6 2-amino-4-benzyl-phenol 
• 6954-93-4 5-benzylquinolin-8-ol 
• 2316-50-9 2-bromo-4,6-dinitrophenol 
• 191096-35-2 Dihydro-3-(4-phenyl-2-nitrophenoxy)-2(3H)-furanone 
• 5464-98-2 (4-hydroxy-3-nitrophenyl)(phenyl)methanone 

Relevant articles and documents

Iodine(III)-Catalyzed Electrophilic Nitration of Phenols via Non-Br?nsted Acidic NO2+ Generation

The first catalytic procedure for the electrophilic nitration of phenols was developed using iodosylbenzene as an organocatalyst based on iodine(III) and aluminum nitrate as a nitro group source. This atom-economic protocol occurs under mild, non-Br?nsted acidic and open-flask reaction conditions with a broad functional-group tolerance including several heterocycles. Density functional theory (DFT) calculations at the (SMD:MeCN)Mo8-HX/(LANLo8+f,6-311+G) level indicated that the reaction proceeds through a cationic pathway that efficiently generates the NO2+ ion, which is the nitrating species under neutral conditions.

Nitration of arenes by 1-sulfopyridinium nitrate as an ionic liquid and reagent by in situ generation of NO2

1-Sulfopyridinium nitrate was synthesized as a potent nitrating agent for the nitration of arenes without the need for any co-catalysts. A variety of nitro compounds were synthesized and fully characterized by IR, 1H NMR, 13C NMR, thermal gravimetric analysis (TGA), differential thermal gravimetry (DTG), CHN analysis and mass spectroscopy. Mechanistically, in situ generated nitrogen dioxide as a radical from the reagent is proposed for the presented nitration protocol.

Nitration of phenolic compounds and oxidation of hydroquinones using tetrabutylammonium chromate and dichromate under aprotic conditions

In this work, we have reported a mild, efficient and selective method for the mononitration of phenolic compounds using sodium nitrite in the presence of tetrabutylammonium dichromate (TBAD) and oxidation of hydroquinones to quinones with TBAD in CH2Cl2. Using this method, high yields of nitrophenols and quinones were obtained under neutral aprotic conditions. Tetrabutylammonium chromate (TBAC) can also be used as oxidant at same conditions. Indian Academy of Sciences.