37053-62-6

Upstream product

• 631-61-8 ammonium acetate 
• 555-16-8 4-nitrobenzaldehdye 
• 84-11-7 9,10-phenanthrenequinone 
• 134-81-6 benzil 
• 57-13-6 urea 

Downstream Products

• 1377617-70-3 4-(1-hexyl-1H-phenanthro[9,10-d]imidazol-2-yl)aniline 
• 1377617-69-0 1-hexyl-2-(4-nitrophenyl)-1H-phenanthro[9,10-d]imidazole 
• 1415133-28-6 4-(1-butyl-1H-phenanthro[9,10-d]imidazol-2-yl)aniline 
• 1415133-27-5 1-butyl-2-(4-nitrophenyl)-1H-phenanthro[9,10-d]imidazole 

Relevant academic research and scientific papers

Fluorodynamers Displaying Tunable Fluorescence on Constitutional Exchanges in Solution and at Solid Film–Solution Interface

Dynamic covalent polymers—dynamers—are adaptive materials that offer timely variant adaptive macroscopic organization across extended scales. In the current study, imine exchange reactions and fluorescence transfer can occur at the interfaces between vari

Urea-Zinc Chloride Eutectic Mixture-Mediated One-Pot Synthesis of Imidazoles: Efficient and Ecofriendly Access to Trifenagrel

The low-melting mixture urea-ZnCl 2 was evaluated as a novel reaction medium for the synthesis of imidazoles. The reaction between a dicarbonyl compound, ammonium acetate, and an aromatic aldehyde is efficiently catalyzed by the eutectic solvent, yielding a wide variety of triaryl-1 H -imidazoles or 2-aryl-1 H -phenanthro[9,10- d ]imidazoles in good to excellent yields. In addition, the eutectic solvent was reused in five cycles without loss of its catalytic activity. This protocol was further explored for the synthesis of the drug trifenagrel, giving an excellent yield.

Citrate trisulfonic acid: A heterogeneous organocatalyst for the synthesis of highly substituted Imidazoles

Citrate trisulfonic acid (CTSA), as a novel recyclable and eco-benign organocatalyst, was employed for the efficient and one-pot synthesis of trisubstituted imidazoles and tetrasubstituted imidazoles using aldehydes, ammonium acetate or aniline, and benzoin, benzyl, or 9,10-phenanthrenequinone under solvent-free conditions providing high to excellent yields. CTSA is easily prepared via the reaction of trisodium citrate and chlorosulfonic acid in high purity. Compared to the conventional procedures, the present method offers several advantages, including high yields, easy work-up, short reaction time, reusability of the catalyst, and simple purification of the products.

Efficientone-pot synthesis of imidazoles catalyzed by silica-supported La0.5Pb0.5MnO3 nano particles as anovel and reusable perovskite oxide

Silica-supported La0.5Pb0.5MnO3 nanoparticles was prepared and used as a new perovskite-type catalyst for rapid and efficient synthesis of substituted imidazoles by an one-pot three-component condensation of [9,10]-phenanthraquinone, aryl aldehydes and ammonium acetate in excellent yield under reflux, and also solvent-free conditions.

Preparation, Characterization, and Application of Preyssler Heteropoly Acid Immobilized on Magnetic Nanoparticles as a Green and Recoverable Catalyst for the Synthesis of Imidazoles

An efficient, magnetically separable catalyst was synthesized by immobilization of Preyssler heteropoly acid (HPA) on Ni0.5Zn0.5Fe2O4 magnetite nanoparticles (MNPs) coated with hydroxyapatite (HA). The catalyst was characterized by scaning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), FT-IR, energy dispersive spectroscopy (EDS), and TGA. Activity of this catalyst was tested in the synthesis of imidazole derivatives via one-pot three-component condensation of [9,10]-phenanthraquinone with aryl aldehydes and ammonium acetate at room temperature under solvent-free conditions.

Novel reversible colorimetric ratio benzimidazole fluorescent molecular probe for detecting palladium

The invention discloses a novel reversible colorimetric ratio benzimidazole fluorescent molecular probe for detecting palladium and relates to synthesis and application of the fluorescent molecular probe. The molecule of the fluorescent probe is allyl(4-(1-(2-(2-(2-methoxyl ethoxyl)ethoxyl)ethyl)-1H-phenanthro[9,10-d] imidazole-2-yl) phenyl) which is prepared by a reaction on (4-(1-(2-(2-(2-methoxyl ethoxyl)ethoxyl)ethyl)-1H-phenanthro[9,10-d] imidazole-2-yl) aniline and AllocCl. The fluorescent molecular probe is dissolved in an aqueous solution of acetonitrile to test change of the absorbance value and fluorescence intensity to determine the content of palladium behind and after a sample is added. The detection limit is as low as 2.9nM, and the fluorescent molecular probe can be used for detecting palladium in an environment or a living body.

Specific receptor for hydrazine: Mapping the: In situ release of hydrazine in live cells and in an in vitro enzymatic assay

We report a new chemodosimetric reagent capable of detecting hydrazine in the presence of several other competing amine derivatives and ionic analytes of biological relevance. This reagent has been utilized for real time monitoring of in situ N2/sub

Multi-component synthesis of highly substituted imidazoles catalyzed by nanorod vanadatesulfuric acid

Nanorod vanadatesulfuric acid (VSA NRs), as a recyclable and eco-benign catalyst, was used for one-pot synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles using aldehydes, benzil, benzoin or 9,10-phenanthrenequinone and ammonium acetate or aniline under solvent-free conditions providing high to excellent yields. VSA is easily prepared by a simple reaction of chlorosulfonic acid and sodium metavanadate in high purity. As compared with the conventional procedures, the present protocol offers several advantages such as simplicity of procedure, short reaction time, high yields, easy workup, recoverability and reusability of the catalyst and simple purification of the products.

A novel imidazolium-based acidic ionic liquid as an efficient and reusable catalyst for the synthesis of 2-aryl-1H-phenanthro[9,10-d]imidazoles

A novel acidic ionic liquid based on imidazoliumcation is designed, synthesized, and successfully used as a catalyst for the one-pot synthesis of 2-aryl-1H-phenanthro[9,10-d]imidazole derivatives. The remarkable feature of this new catalyst is its ethyleneoxy bridge which participates in dissolving organic compounds in ionic liquids. The application of this acidic ionic liquid is studied in a new one-pot method for the synthesis of imidazole derivatives under solvent-free conditions. The advantages of this method are the reusability of the catalyst, high conversion, short reaction time, and simple experimental procedure.

Study on the synthesis and structure-effect relationship of multi-aryl imidazoles with their fluorescence properties

In this paper, 23 multi-aryl imidazole derivatives were synthesized and identified by nuclear magnetic resonance, ultraviolet-visible and elemental analysis. At the same time, their ultraviolet-visible maximum absorption (λabmax), fluorescence emission maximum (λemmax) and quantum yields (Cyrillic capital letter eff) were measured. The relationships between the optical behaviors and structures for these compounds were assessed. The results show that the λmaxab and λmax em are red-shifted and the fluorescence Cyrillic capital letter eff are increased by the introduction of electron-withdrawing substituents and the increase in the planarity of multi-aryl imidazole molecules. The results also showed that the fluorescence quantum yields of the compounds containing two imidazole nuclei are double the corresponding mono-imidazole nucleus compounds. Copyright