370554-12-4

Downstream Products

• 370554-13-5 phenyl 2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-1-thio-β-D-galactopyranoside 
• 370554-15-7 O-(2-azido-3,4-di-O-benzyl-2-deoxy-α-D-galactopyranosyl)-N-(benzyloxycarbonyl)-L-serine benzyl ester 
• 370554-14-6 O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-galactopyranosyl)-N-(benzyloxycarbonyl)-L-serine benzyl ester 

Relevant academic research and scientific papers

A convergent total synthesis of the mucin related F1α antigen by one-pot sequential stereoselective glycosylation

A convergent total synthesis of F1α antigen, a member of the tumor-associated O-linked mucin glycosyl amino acids, was accomplished by one-pot sequential glycosylation. In the first step, the corresponding disaccharide was formed from galactosyl phenylcarbonate 2 or fluoride 3 and thioglycoside 4 by the promotion of TrB(C6F5)4 or TfOH, and following glycosylation of glycosyl amino acid 5 by further addition of N-iodosuccinimide(NIS) afforded protected F1α in 80 or 89% overall yield, respectively. By the subsequent deprotection, F1α antigen was obtained in good yield.