370562-35-9

Usage

Uses

Used in Food Industry:
METHYL 2-PYRAZINEACETATE is used as a flavoring agent for imparting savory and meaty flavors to various food products. Its unique aroma profile is ideal for enhancing the taste of seasonings, sauces, and snack foods, contributing to a richer and more complex flavor experience.
Used in Fragrance Industry:
In the fragrance industry, METHYL 2-PYRAZINEACETATE is utilized as a component in perfumes and colognes, adding depth and a distinctive scent to these products. Its ability to provide a long-lasting and pleasant aroma makes it a sought-after ingredient in the formulation of various fragrances.
Regulatory Approval:
METHYL 2-PYRAZINEACETATE is considered safe for use in both food and fragrance applications. It has been approved for use by regulatory authorities in various countries, ensuring its compliance with safety standards and consumer protection regulations.

InChI:InChI=1/C7H8N2O2/c1-11-7(10)4-6-5-8-2-3-9-6/h2-3,5H,4H2,1H3

Upstream product

• 109-08-0 2-Methylpyrazine 
• 79-22-1 methyl chloroformate 
• 616-38-6 carbonic acid dimethyl ester 

Downstream Products

• 1341956-76-0 methyl 2-(pyrazin-2-yl)propanoate 
• 934172-14-2 2-(pyrazin-2-yl)acetohydrazide 

Relevant academic research and scientific papers

Copper-Catalyzed Bisannulations of Malonate-Tethered O-Acyl Oximes with Pyridine, Pyrazine, Pyridazine, and Quinoline Derivatives for the Construction of Dihydroindolizine-Fused Pyrrolidinones and Analogues

A copper-catalyzed bisannulation reaction of malonate-tethered O-acyl oximes with pyridine, pyrazine, pyridazine, and quinoline derivatives has been developed for the concise synthesis of structurally novel dihydroindolizine-fused pyrrolidinones and their analogues. The present reaction shows excellent regioselectivity and stereoselectivity. Theoretical calculations reveal that the coordination effect of the carbonyl group in the nucleophilic substrate determines the excellent regioselectivity. Further functionalization of the generated dihydroindolizine-fused pyrrolidinone could be easily realized through substitution, Michael addition, selective aminolysis, and hydrolysis reactions.

RhIII-Catalyzed C-H Activation with Pyridotriazoles: Direct Access to Fluorophores for Metal-Ion Detection

The first C-H bond activation with pyridotriazoles as coupling partners is presented using a RhIII catalyst. The pyridotriazoles can be used as new carbene precursors in C-H activation for direct access to novel fluorescent scaffolds. These tunable fluorophores can be applied for the detection of metal ions.

Palladium-catalyzed decarboxylative couplings of 2-(2-Azaaryl)acetates with aryl halides and triflates

Pd-catalyzed decarboxylative cross-couplings of 2-(2-azaaryl)acetates with aryl halides and triflates have been discovered. This reaction is potentially useful for the synthesis of some functionalized pyridines, quinolines, pyrazines, benzoxazoles, and benzothiazoles. Theoretical analysis shows that the nitrogen atom at the 2-position of the heteroaromatics directly coordinates to Pd(II) in the decarboxylation transition state.

Catalytic asymmetric cyclopropanation of heteroaryldiazoacetates

Rh2(S-DOSP)4-catalyzed decomposition of heteroaryldiazoacetates in the presence of styrene results in highly diastereoselective and enantioselective cyclopropanations. Heteroaryldiazoacetates containing both electron-rich and electron-deficient heterocycles, such as thiophene, furan, pyridine, indole, oxazole, isoxazole, and benzoxazole, are effective in this chemistry. These studies broaden the range of diazo compounds containing both electron-withdrawing and electron-donating groups, which undergo highly diastereoselective cyclopropanations.