37059-43-1

Basic information

• Product Name: 4,6-DIPYRROLIDIN-1-YL-1,3,5-TRIAZIN-2-OL
• Synonyms: 4,6-DIPYRROLIDIN-1-YL-1,3,5-TRIAZIN-2-OL
• CAS NO: 37059-43-1
• Molecular Formula: C₁₁H₁₇N₅O
• Molecular Weight: 235.29
• Mol File: 37059-43-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,6-DIPYRROLIDIN-1-YL-1,3,5-TRIAZIN-2-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-DIPYRROLIDIN-1-YL-1,3,5-TRIAZIN-2-OL(37059-43-1)
• EPA Substance Registry System: 4,6-DIPYRROLIDIN-1-YL-1,3,5-TRIAZIN-2-OL(37059-43-1)

Safety Data

• Hazardous Substances Data: 37059-43-1(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 108-80-5 cyanuric acid 

Relevant articles and documents

Amination, III. Trimethylsilanol as Leaving Group, V. Silylation - Amination of Hydroxy N-Heterocycles

Hydroxy N-heterocycles such as 18, 21, 26, and others are efficiently aminated in a one-step/one-pot procedure by silylation-amination to give 20, 23 - 25 etc.Silylation converts aromatic hydroxy N-heterocycles into activated and lipophilic intermediates of type 3, 8 which react in situ with ammonia, primary or secondary amines to form the corresponding mono-, bis- or tris-aminated products (5, 10).This addition-elimination of amines to O-silylated heterocycles is Lewis acid-catalysed and proceeds usually in high yields if the leaving group trimethylsilanol is converted in situ by excess silylated agent into hexamethyldisiloxane.Scope and limitations of this simple procedure are discussed.