37060-27-8 Usage
Type of compound
Heterocyclic aromatic compound 1H-Pyrazole, 3-(1,3-benzodioxol-5-yl)-5-phenyl- has a pyrazole ring in its structure, which is a five-membered ring containing two heteroatoms (atoms other than carbon) and is characterized by its aromatic properties.
Pyrazole ring
A five-membered ring with two heteroatoms The pyrazole ring is a key structural feature of 1H-Pyrazole, 3-(1,3-benzodioxol-5-yl)-5-phenyl-, which contributes to its chemical and biological properties.
Substituents
1,3-benzodioxole group and phenyl group The pyrazole ring in 1H-Pyrazole, 3-(1,3-benzodioxol-5-yl)-5-phenyl- is substituted with a 1,3-benzodioxole group (a bicyclic structure with one oxygen atom in a three-membered ring and two oxygen atoms in a five-membered ring) and a phenyl group (a six-membered carbon ring with alternating single and double bonds), which influence its pharmacological and biological activities.
Pharmacological and biological activities
1H-Pyrazole, 3-(1,3-benzodioxol-5-yl)-5-phenyl- has been studied for its various pharmacological and biological activities, making it a potential candidate for medicinal chemistry applications.
Anticonvulsant properties
1H-Pyrazole, 3-(1,3-benzodioxol-5-yl)-5-phenylhas been found to exhibit anticonvulsant properties, which may make it useful in the development of new drugs for neurological conditions such as epilepsy.
Analgesic properties
1H-Pyrazole, 3-(1,3-benzodioxol-5-yl)-5-phenyl- also has analgesic (pain-relieving) properties, suggesting its potential use in the treatment of pain-related conditions.
Anti-inflammatory properties
In addition to its other properties, 1H-Pyrazole, 3-(1,3-benzodioxol-5-yl)-5-phenylmay also possess anti-inflammatory properties, which can be beneficial in reducing inflammation and promoting healing in various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 37060-27-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,0,6 and 0 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 37060-27:
(7*3)+(6*7)+(5*0)+(4*6)+(3*0)+(2*2)+(1*7)=98
98 % 10 = 8
So 37060-27-8 is a valid CAS Registry Number.
37060-27-8Relevant academic research and scientific papers
Nigam, Sandeep,Joshi,Joshi
, p. 405 - 410 (2003)
Reactions of various, diaryl 1,3-diketones (1a-1i) with hydrazine hydrate in absolute ethanol led to the formation of corresponding pyrazole derivatives (2a-2i). Structures of these compounds were established on the basis of spectral studies viz. elementa
Synthesis of 3,5-diphenyl-1H-pyrazoles
Bhat,Puri,Qurishi,Dhar,Qazi
, p. 1135 - 1142 (2007/10/03)
An efficient and convenient synthesis of 3,5-diphenyl-1N-pyrazoles from chalcones by the action of hydrazine hydrate on chalcone-epoxide followed by simultaneous dehydration is reported. Copyright Taylor & Francis, Inc.
Reaction of Acetylenic Ketones with Hydrazine Derivatives. Synthesis of Hydroxypyrazoles
Al-Hajjar, Farouk S.,Sabri, Salim S.
, p. 727 - 729 (2007/10/02)
Aroylphenylacetylenes Ia-c react with t-butyl hydrazinecarboxylates (IIa) and 2-furylhydrazide(IIb) to give the corresponding hydroxydihydropyrazole derivatives IVa-f.This cyclic structure is supported by chemical transformations.Thus, when compounds IVa-c are heated with acetic anhydride, they yield the corresponding 5-aryl-1-(t-butoxycarbonyl)-3-phenylpyrazoles Va-c which, upon hydrolysis with methanolic potassium hydroxide, produce the corresponding 5(3)aryl-3(5)phenylpyrazoles VI.Spectroscopic data also confirm the suggested cyclic structure IV.
