37061-97-5

Upstream product

• 98-88-4 benzoyl chloride 
• 79416-27-6 methyl aminolevulinate 
• 1490-25-1 succinic acid monomethylester chloride 
• 1199-01-5 2-phenylazlactone 
• 37061-89-5 succinic acid methyl ester 2-phenyl-oxazol-5-yl ester 
• 495-69-2 Hippuric Acid 
• 75-11-6 diiodomethane 
• 68661-22-3 methyl 4-(N-benzoyl)amino-3-oxobutanoate 
• 29491-94-9 2-phenyl-4-(β-carbomethoxypropionyl)oxazolin-5-one 

Downstream Products

• 1204423-32-4 C₁₃H₁₃NO₂S 
• 933692-98-9 3-(2-Phenylthiazol-5-yl)propionic acid 

Relevant academic research and scientific papers

Photoassisted diversity-oriented synthesis: Intramolecular cycloadditions of photogenerated azaxylylenes with oxazole pendants, and subsequent postphotochemical multicomponent modifications

Photogenerated aza-o-xylylenes undergo intramolecular cycloaddition reactions to tethered oxazoles, with primary photoproducts featuring a reactive cyclic imine moiety suitable for multicomponent postphotochemical transformations. For example, the reactio

NITROGEN-CONTAINING AROMATIC HETEROCYCLYL COMPOUND

The present invention provides a compound having excellent regulating action on blood lipid level. The present invention provides a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof, etc., wherein A represents a 5-membered nitrogen-containing aromatic heterocyclyl group; R1 represents COOH or the like; each R2 represents an alkyl or the like; each R3 represents an optionally substituted phenyl, an optionally substituted phenylalkyl, or the like; m represents 0, 1, 2, or 3; n represents 0 or 1; each of R4, R5, R6, and R7 represents H, an alkyl, or the like; and B represents an optionally substituted naphthyl, an optionally substituted aromatic heterocyclyl, or a group represented by the following formula (II) wherein each of B1 and B2 represents an optionally substituted phenyl or an optionally substituted aromatic heterocyclyl.

Chain extension of amino acid skeletons: Preparation of ketomethylene isosteres

Ketomethylene isosteric replacements for peptide bonds were generated through a zinc carbenoid-mediated chain extension reaction in which a variety of amino acid-derived β-keto esters are converted to γ-keto esters in a single step. The reaction tolerates a variety of protecting groups and amino acid side chains with no epimerization of the amino acid stereocenter.