37067-52-0Relevant academic research and scientific papers
Resolution of racemic aryl dichloromethyl sulfoxides with (-)-menthone
Noguchi, Takafumi,Miyagawa, Toshifumi,Satoh, Tsuyoshi
body text, p. 2073 - 2076 (2010/03/01)
The addition reaction of the sodium α-sulfinyl carbanion of a racemic aryl dichloromethyl sulfoxide to (-)-menthone in the presence of boron trifluoride diethyl etherate gave an adduct as a mixture of two easily separable diastereomers. After separation of the diastereomers, they were each treated with sodium hydride to afford enantiomerically pure aryl dichloromethyl sulfoxides and (-)-menthone both in high yields. This procedure provides a simple and efficient method for the resolution of racemic aryl dichloromethyl sulfoxides.
Facile one-pot synthesis of α-chloro sulfoxides from sulfides
Kim,Shin,Park
, p. 209 - 210 (2007/10/02)
Various sulfides 1 reacted with sulfuryl chloride in the presence of metal nitrates in acetonitrile under mild conditions to give the corresponding α-chloro sulfoxides 2 in good yields.
Asymmetric Synthesis of α,α-dichlorosulphoxides from Substituted Thioacetates and Sodium Hypochlorite in β-Cyclodextrin Complexes
Rao, K. Rama,Sattur, P. B.
, p. 342 - 343 (2007/10/02)
The reaction of β-cyclodextrin complexes of substituted thioacetates (1) with sodium hypochlorite in aqueous medium gives optically active α,α-dichlorosulphoxides (2) in good yields with an enantiomeric excess (e.e.) of up to 53percent.
