370857-89-9Relevant academic research and scientific papers
General method for the synthesis of cyclic peptidomimetic compounds
Walker, Michael A.,Johnson, Timothy
, p. 5801 - 5804 (2007/10/03)
A number of cyclic peptides, wherein the i and i+1 residue side chains are joined by an alkyl linker and a Weinreb amide is present at the C-terminus, were synthesized. Using LiCl to solubilize these peptides in THF the C-terminus can be readily converted to an activated carbonyl such as an aldehyde or ketone.
