370866-01-6

Basic information

• Product Name: 1H-Pyrazolo[3,4-b]pyridin-4-ol, 5-bromo-1-[(4-methoxyphenyl)methyl]-
• CAS NO: 370866-01-6
• Molecular Formula: C14H12BrN3O2
• Molecular Weight: 334.172
• Mol File: 370866-01-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazolo[3,4-b]pyridin-4-ol, 5-bromo-1-[(4-methoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazolo[3,4-b]pyridin-4-ol, 5-bromo-1-[(4-methoxyphenyl)methyl]-(370866-01-6)
• EPA Substance Registry System: 1H-Pyrazolo[3,4-b]pyridin-4-ol, 5-bromo-1-[(4-methoxyphenyl)methyl]-(370866-01-6)

Safety Data

• Hazardous Substances Data: 370866-01-6(Hazardous Substances Data)

Upstream product

• 924909-16-0 1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-ol 
• 227617-15-4 4-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester 
• 370865-99-9 4-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid 
• 3528-45-8 1-(4-methoxybenzyl)-1H-pyrazol-5-amine 
• 924909-16-0 1-(4-methoxy-benzyl)-1,7-dihydro-pyrazolo[3,4-b]pyridin-4-one 

Downstream Products

• 1173067-77-0 tert-butyl 4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)piperazine-1-carboxylate 
• 1034769-88-4 5-bromo-4-chloro-1H-pyrazolo[3,4-b]pyridine 
• 370866-02-7 5-bromo-4-chloro-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridine 
• 370866-04-9 4-butoxy-1-(4-methoxy-benzyl)-5-phenylsulfanyl-1H-pyrazolo[3,4-b]pyridine 
• 370866-03-8 5-Bromo-4-butoxy-1-[(4-methoxyphenyl)methyl]-1H-pyrazolo [3,4-b]pyridine 
• 370866-05-0 4-butoxy-5-phenylsulfanyl-1H-pyrazolo[3,4-b]pyridine 

Relevant articles and documents

PYRAZOLOPYRIDINES AS KINASE INHIBITORS

Compounds of Formula I are useful for inhibition of CHK1 and/or CHK2. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

Use of 5-thio-, sulfinyl- and sulfonylpyrazolo[3,4-b]- pyridines as cyclin dependent kinase inhibitors

The present invention describes compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and n are as defined above. Compounds of formula (I) are protein kinase inhibitors